The impact of optical radiation of femtosecond duration on human glial cells

Diana B. Ilatovskaia*, Yuri B. Porozov, Petr S. Demchenko, Igor V. Meglinski, Mikhail K. Khodzitsky

*Corresponding author for this work

Research output: Contribution to journalConference articlepeer-review


The paper presents the results of the studies of influence of optical radiation with wavelengths of 520 and 780 nm on human glial cells (U251) at the range of exposure times ∼ 1-15 min. It was found that after the first minute of irradiation at the wavelength of 780 nm, the relative number of apoptotic cells significantly increased. The result corroborates the concept of biological hazard of optical radiation for tumor cells, and suggests that the approach has a great potential in clinical application for the treatment of human glioma.

Original languageEnglish
Article number108203G
JournalProceedings of SPIE - International Society for Optical Engineering
Publication statusPublished - 23 Oct 2018
EventOptics in Health Care and Biomedical Optics VIII 2018 - Beijing, China
Duration: 11 Oct 201813 Oct 2018

Bibliographical note

Copyright 2018 SPIE. One print or electronic copy may be made for personal use only. Systematic reproduction, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.


  • apoptosis
  • cell line U251
  • cytochrome C oxidase
  • glioma
  • Irradiation
  • pulse IR radiation
  • resonance effect


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