The impact of optical radiation of femtosecond duration on human glial cells

Diana B. Ilatovskaia; Yuri B. Porozov; Petr S. Demchenko; Igor V. Meglinski; Mikhail K. Khodzitsky

doi:10.1117/12.2502601

The impact of optical radiation of femtosecond duration on human glial cells

Diana B. Ilatovskaia^*, Yuri B. Porozov, Petr S. Demchenko, Igor V. Meglinski, Mikhail K. Khodzitsky

^*Corresponding author for this work

Research output: Contribution to journal › Conference article › peer-review

Abstract

The paper presents the results of the studies of influence of optical radiation with wavelengths of 520 and 780 nm on human glial cells (U251) at the range of exposure times ∼ 1-15 min. It was found that after the first minute of irradiation at the wavelength of 780 nm, the relative number of apoptotic cells significantly increased. The result corroborates the concept of biological hazard of optical radiation for tumor cells, and suggests that the approach has a great potential in clinical application for the treatment of human glioma.

Original language	English
Article number	108203G
Journal	Proceedings of SPIE - International Society for Optical Engineering
Volume	10820
DOIs	https://doi.org/10.1117/12.2502601
Publication status	Published - 23 Oct 2018
Event	Optics in Health Care and Biomedical Optics VIII 2018 - Beijing, China Duration: 11 Oct 2018 → 13 Oct 2018

Bibliographical note

Copyright 2018 SPIE. One print or electronic copy may be made for personal use only. Systematic reproduction, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.

Keywords

apoptosis
cell line U251
cytochrome C oxidase
glioma
Irradiation
pulse IR radiation
resonance effect

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The impact of optical radiation of femtosecond duration on human glial cellsFinal published version, 379 KB

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title = "The impact of optical radiation of femtosecond duration on human glial cells",

abstract = "The paper presents the results of the studies of influence of optical radiation with wavelengths of 520 and 780 nm on human glial cells (U251) at the range of exposure times ∼ 1-15 min. It was found that after the first minute of irradiation at the wavelength of 780 nm, the relative number of apoptotic cells significantly increased. The result corroborates the concept of biological hazard of optical radiation for tumor cells, and suggests that the approach has a great potential in clinical application for the treatment of human glioma.",

keywords = "apoptosis, cell line U251, cytochrome C oxidase, glioma, Irradiation, pulse IR radiation, resonance effect",

author = "Ilatovskaia, {Diana B.} and Porozov, {Yuri B.} and Demchenko, {Petr S.} and Meglinski, {Igor V.} and Khodzitsky, {Mikhail K.}",

note = "Copyright 2018 SPIE. One print or electronic copy may be made for personal use only. Systematic reproduction, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited. ; Optics in Health Care and Biomedical Optics VIII 2018 ; Conference date: 11-10-2018 Through 13-10-2018",

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AU - Ilatovskaia, Diana B.

AU - Porozov, Yuri B.

AU - Demchenko, Petr S.

AU - Meglinski, Igor V.

AU - Khodzitsky, Mikhail K.

N1 - Copyright 2018 SPIE. One print or electronic copy may be made for personal use only. Systematic reproduction, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.

PY - 2018/10/23

Y1 - 2018/10/23

N2 - The paper presents the results of the studies of influence of optical radiation with wavelengths of 520 and 780 nm on human glial cells (U251) at the range of exposure times ∼ 1-15 min. It was found that after the first minute of irradiation at the wavelength of 780 nm, the relative number of apoptotic cells significantly increased. The result corroborates the concept of biological hazard of optical radiation for tumor cells, and suggests that the approach has a great potential in clinical application for the treatment of human glioma.

AB - The paper presents the results of the studies of influence of optical radiation with wavelengths of 520 and 780 nm on human glial cells (U251) at the range of exposure times ∼ 1-15 min. It was found that after the first minute of irradiation at the wavelength of 780 nm, the relative number of apoptotic cells significantly increased. The result corroborates the concept of biological hazard of optical radiation for tumor cells, and suggests that the approach has a great potential in clinical application for the treatment of human glioma.

KW - apoptosis

KW - cell line U251

KW - cytochrome C oxidase

KW - glioma

KW - Irradiation

KW - pulse IR radiation

KW - resonance effect

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DO - 10.1117/12.2502601

M3 - Conference article

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VL - 10820

JO - Proceedings of SPIE - International Society for Optical Engineering

JF - Proceedings of SPIE - International Society for Optical Engineering

M1 - 108203G

T2 - Optics in Health Care and Biomedical Optics VIII 2018

Y2 - 11 October 2018 through 13 October 2018

ER -

The impact of optical radiation of femtosecond duration on human glial cells

Abstract

Bibliographical note

Keywords

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