Tunable Ag@SiO2 core-shell nanocomposites for broad spectrum antibacterial applications

Mark A. Isaacs, Lee J. Durndell, Anthony C. Hilton, Luca Olivi, Christopher M.A. Parlett, Karen Wilson*, Adam F. Lee

*Corresponding author for this work

Research output: Contribution to journalArticle

Abstract

Silica encapsulated silver nanoparticle core-shell nanocomposites of tunable dimensions were synthesised via a one-pot reverse microemulsion route to achieve controlled release of Ag+ ions for broad spectrum antibacterial application. Silver release rates and bactericidal efficacy against Gram-positive and Gram-negative bacteria, S. aureus and P. aeruginosa respectively, were inversely proportional to nanoparticle core diameter (3-8 nm) and silica shell (7-14 nm) thickness, and readily tuned through a facile hydrothermal etching protocol employing a PVP stabiliser to introduce mesoporosity.

Original languageEnglish
Pages (from-to)23342-23347
Number of pages6
JournalRSC advances
Volume7
Issue number38
DOIs
Publication statusPublished - 27 Apr 2017

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Silver
Silicon Dioxide
Nanocomposites
Silica
Nanoparticles
Microemulsions
Etching
Bacteria
Ions

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This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Cite this

Isaacs, M. A., Durndell, L. J., Hilton, A. C., Olivi, L., Parlett, C. M. A., Wilson, K., & Lee, A. F. (2017). Tunable Ag@SiO2 core-shell nanocomposites for broad spectrum antibacterial applications. RSC advances, 7(38), 23342-23347. https://doi.org/10.1039/c7ra03131a
Isaacs, Mark A. ; Durndell, Lee J. ; Hilton, Anthony C. ; Olivi, Luca ; Parlett, Christopher M.A. ; Wilson, Karen ; Lee, Adam F. / Tunable Ag@SiO2 core-shell nanocomposites for broad spectrum antibacterial applications. In: RSC advances. 2017 ; Vol. 7, No. 38. pp. 23342-23347.
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Isaacs, MA, Durndell, LJ, Hilton, AC, Olivi, L, Parlett, CMA, Wilson, K & Lee, AF 2017, 'Tunable Ag@SiO2 core-shell nanocomposites for broad spectrum antibacterial applications', RSC advances, vol. 7, no. 38, pp. 23342-23347. https://doi.org/10.1039/c7ra03131a

Tunable Ag@SiO2 core-shell nanocomposites for broad spectrum antibacterial applications. / Isaacs, Mark A.; Durndell, Lee J.; Hilton, Anthony C.; Olivi, Luca; Parlett, Christopher M.A.; Wilson, Karen; Lee, Adam F.

In: RSC advances, Vol. 7, No. 38, 27.04.2017, p. 23342-23347.

Research output: Contribution to journalArticle

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Isaacs MA, Durndell LJ, Hilton AC, Olivi L, Parlett CMA, Wilson K et al. Tunable Ag@SiO2 core-shell nanocomposites for broad spectrum antibacterial applications. RSC advances. 2017 Apr 27;7(38):23342-23347. https://doi.org/10.1039/c7ra03131a