Visual Outcomes After Cataract Surgery

Multifocal Versus Monofocal Intraocular Lenses

Sunil Shah, Cristina Peris-Martinez, Thomas Reinhard, Paolo Vinciguerra

Research output: Contribution to journalArticle

Abstract

PURPOSE: To evaluate visual outcomes, spectacle independence, and quality of life among nonastigmatic and astigmatic patients who received AcrySof IQ ReSTOR toric or nontoric multifocal intraocular lenses (IOLs) (Alcon Laboratories, Fort Worth, TX) compared with those who received commercially available nontoric monofocal IOLs after bilateral cataract removal.

METHODS: This randomized, patient- and observer-technician-masked study was conducted at 20 sites in Europe. Patients were randomized to receive monofocal (nontoric only) or multifocal (nontoric or toric, as needed) IOLs. Primary efficacy endpoints included percentage of patients achieving binocular uncorrected distance and near acuity of 0.1 logMAR or better (20/25 Snellen), spectacle independence, and scores on the National Eye Institute Refractive Error and Quality of Life questionnaire domains. Safety endpoints included adverse events and refractive error within 0.5 and 1.0 diopters.

RESULTS: In the multifocal group (n = 108) versus the monofocal group (n = 100), significantly more patients achieved uncorrected distance and near acuity of 0.1 logMAR or better (45.7% vs 2.1%; P < .0001) and spectacle independence (73.3% vs 25.3%; P < .0001) at 6 months. The percentage of patients who achieved uncorrected distance visual acuity of 20/40 or better at 6 months was 92% in the multifocal group and 97% in the monofocal group. National Eye Institute Refractive Error and Quality of Life scores were significantly better for dependence on correction in the multifocal group (P < .0001) and for glare in the monofocal group (P = .0157); other domain scores were similar between groups. No significant trends in study device-related adverse events were observed.

CONCLUSIONS: Monofocal and multifocal IOLs provided good clinical outcomes. More patients receiving multifocal IOLs attained better uncorrected visual acuity at a range of distances and spectacle independence compared with patients who received monofocal IOLs. Monofocal IOLs were associated with better patient-reported scores for glare compared with multifocal IOLs; however, scores for patient satisfaction were significantly better in the multifocal group.

Original languageEnglish
Pages (from-to)658-666
Number of pages9
JournalJournal of Refractive Surgery
Volume31
Issue number10
DOIs
Publication statusPublished - 14 Oct 2015

Fingerprint

Intraocular Lenses
Cataract
Refractive Errors
National Eye Institute (U.S.)
Glare
Quality of Life
Visual Acuity
Patient Satisfaction
Safety
Equipment and Supplies

Bibliographical note

Copyright 2015, SLACK Incorporated. Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)

Keywords

  • Adult
  • Aged
  • Aged, 80 and over
  • Astigmatism/complications
  • Cataract/complications
  • Double-Blind Method
  • Eyeglasses/statistics & numerical data
  • Female
  • Humans
  • Lens Implantation, Intraocular
  • Lenses, Intraocular
  • Male
  • Middle Aged
  • Patient Satisfaction
  • Phacoemulsification
  • Prospective Studies
  • Prosthesis Design
  • Pseudophakia/physiopathology
  • Quality of Life/psychology
  • Visual Acuity/physiology
  • Young Adult

Cite this

Shah, Sunil ; Peris-Martinez, Cristina ; Reinhard, Thomas ; Vinciguerra, Paolo. / Visual Outcomes After Cataract Surgery : Multifocal Versus Monofocal Intraocular Lenses. In: Journal of Refractive Surgery . 2015 ; Vol. 31, No. 10. pp. 658-666.
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abstract = "PURPOSE: To evaluate visual outcomes, spectacle independence, and quality of life among nonastigmatic and astigmatic patients who received AcrySof IQ ReSTOR toric or nontoric multifocal intraocular lenses (IOLs) (Alcon Laboratories, Fort Worth, TX) compared with those who received commercially available nontoric monofocal IOLs after bilateral cataract removal.METHODS: This randomized, patient- and observer-technician-masked study was conducted at 20 sites in Europe. Patients were randomized to receive monofocal (nontoric only) or multifocal (nontoric or toric, as needed) IOLs. Primary efficacy endpoints included percentage of patients achieving binocular uncorrected distance and near acuity of 0.1 logMAR or better (20/25 Snellen), spectacle independence, and scores on the National Eye Institute Refractive Error and Quality of Life questionnaire domains. Safety endpoints included adverse events and refractive error within 0.5 and 1.0 diopters.RESULTS: In the multifocal group (n = 108) versus the monofocal group (n = 100), significantly more patients achieved uncorrected distance and near acuity of 0.1 logMAR or better (45.7{\%} vs 2.1{\%}; P < .0001) and spectacle independence (73.3{\%} vs 25.3{\%}; P < .0001) at 6 months. The percentage of patients who achieved uncorrected distance visual acuity of 20/40 or better at 6 months was 92{\%} in the multifocal group and 97{\%} in the monofocal group. National Eye Institute Refractive Error and Quality of Life scores were significantly better for dependence on correction in the multifocal group (P < .0001) and for glare in the monofocal group (P = .0157); other domain scores were similar between groups. No significant trends in study device-related adverse events were observed.CONCLUSIONS: Monofocal and multifocal IOLs provided good clinical outcomes. More patients receiving multifocal IOLs attained better uncorrected visual acuity at a range of distances and spectacle independence compared with patients who received monofocal IOLs. Monofocal IOLs were associated with better patient-reported scores for glare compared with multifocal IOLs; however, scores for patient satisfaction were significantly better in the multifocal group.",
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Visual Outcomes After Cataract Surgery : Multifocal Versus Monofocal Intraocular Lenses. / Shah, Sunil; Peris-Martinez, Cristina; Reinhard, Thomas; Vinciguerra, Paolo.

In: Journal of Refractive Surgery , Vol. 31, No. 10, 14.10.2015, p. 658-666.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Visual Outcomes After Cataract Surgery

T2 - Multifocal Versus Monofocal Intraocular Lenses

AU - Shah, Sunil

AU - Peris-Martinez, Cristina

AU - Reinhard, Thomas

AU - Vinciguerra, Paolo

N1 - Copyright 2015, SLACK Incorporated. Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)

PY - 2015/10/14

Y1 - 2015/10/14

N2 - PURPOSE: To evaluate visual outcomes, spectacle independence, and quality of life among nonastigmatic and astigmatic patients who received AcrySof IQ ReSTOR toric or nontoric multifocal intraocular lenses (IOLs) (Alcon Laboratories, Fort Worth, TX) compared with those who received commercially available nontoric monofocal IOLs after bilateral cataract removal.METHODS: This randomized, patient- and observer-technician-masked study was conducted at 20 sites in Europe. Patients were randomized to receive monofocal (nontoric only) or multifocal (nontoric or toric, as needed) IOLs. Primary efficacy endpoints included percentage of patients achieving binocular uncorrected distance and near acuity of 0.1 logMAR or better (20/25 Snellen), spectacle independence, and scores on the National Eye Institute Refractive Error and Quality of Life questionnaire domains. Safety endpoints included adverse events and refractive error within 0.5 and 1.0 diopters.RESULTS: In the multifocal group (n = 108) versus the monofocal group (n = 100), significantly more patients achieved uncorrected distance and near acuity of 0.1 logMAR or better (45.7% vs 2.1%; P < .0001) and spectacle independence (73.3% vs 25.3%; P < .0001) at 6 months. The percentage of patients who achieved uncorrected distance visual acuity of 20/40 or better at 6 months was 92% in the multifocal group and 97% in the monofocal group. National Eye Institute Refractive Error and Quality of Life scores were significantly better for dependence on correction in the multifocal group (P < .0001) and for glare in the monofocal group (P = .0157); other domain scores were similar between groups. No significant trends in study device-related adverse events were observed.CONCLUSIONS: Monofocal and multifocal IOLs provided good clinical outcomes. More patients receiving multifocal IOLs attained better uncorrected visual acuity at a range of distances and spectacle independence compared with patients who received monofocal IOLs. Monofocal IOLs were associated with better patient-reported scores for glare compared with multifocal IOLs; however, scores for patient satisfaction were significantly better in the multifocal group.

AB - PURPOSE: To evaluate visual outcomes, spectacle independence, and quality of life among nonastigmatic and astigmatic patients who received AcrySof IQ ReSTOR toric or nontoric multifocal intraocular lenses (IOLs) (Alcon Laboratories, Fort Worth, TX) compared with those who received commercially available nontoric monofocal IOLs after bilateral cataract removal.METHODS: This randomized, patient- and observer-technician-masked study was conducted at 20 sites in Europe. Patients were randomized to receive monofocal (nontoric only) or multifocal (nontoric or toric, as needed) IOLs. Primary efficacy endpoints included percentage of patients achieving binocular uncorrected distance and near acuity of 0.1 logMAR or better (20/25 Snellen), spectacle independence, and scores on the National Eye Institute Refractive Error and Quality of Life questionnaire domains. Safety endpoints included adverse events and refractive error within 0.5 and 1.0 diopters.RESULTS: In the multifocal group (n = 108) versus the monofocal group (n = 100), significantly more patients achieved uncorrected distance and near acuity of 0.1 logMAR or better (45.7% vs 2.1%; P < .0001) and spectacle independence (73.3% vs 25.3%; P < .0001) at 6 months. The percentage of patients who achieved uncorrected distance visual acuity of 20/40 or better at 6 months was 92% in the multifocal group and 97% in the monofocal group. National Eye Institute Refractive Error and Quality of Life scores were significantly better for dependence on correction in the multifocal group (P < .0001) and for glare in the monofocal group (P = .0157); other domain scores were similar between groups. No significant trends in study device-related adverse events were observed.CONCLUSIONS: Monofocal and multifocal IOLs provided good clinical outcomes. More patients receiving multifocal IOLs attained better uncorrected visual acuity at a range of distances and spectacle independence compared with patients who received monofocal IOLs. Monofocal IOLs were associated with better patient-reported scores for glare compared with multifocal IOLs; however, scores for patient satisfaction were significantly better in the multifocal group.

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KW - Aged

KW - Aged, 80 and over

KW - Astigmatism/complications

KW - Cataract/complications

KW - Double-Blind Method

KW - Eyeglasses/statistics & numerical data

KW - Female

KW - Humans

KW - Lens Implantation, Intraocular

KW - Lenses, Intraocular

KW - Male

KW - Middle Aged

KW - Patient Satisfaction

KW - Phacoemulsification

KW - Prospective Studies

KW - Prosthesis Design

KW - Pseudophakia/physiopathology

KW - Quality of Life/psychology

KW - Visual Acuity/physiology

KW - Young Adult

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DO - 10.3928/1081597X-20150611-01

M3 - Article

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JO - Journal of Refractive Surgery

JF - Journal of Refractive Surgery

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