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Personal profile

General

I have been in my current role as lecturer in pharmaceutics since 2010, although I have an even longer history with Aston University.

First of all, I studied here for a BSc in Combined Honours Chemistry and French, graduating in 2004, part of which involved a sandwich year in a university research laboratory in Montpellier, France; this experience whetted my appetite to pursue a career within academic research.

Subsequently, I then studied for a PhD on the subject of formulation and characterisation of particulate delivery systems for TB vaccines, again at Aston University, under the supervision of Prof. Yvonne Perrie.

Before taking up my current role, I was an Aston based post-doc, acting as Formulation Research Fellow for the UK Medicines for Children Research Network.

Research Interests

Based within the pharmaceutics laboratories of Aston Pharmacy School, my main area of research is the formulation of age-appropriate medicines for the extremes of life - paediatric and geriatric populations - with a focus on the identification of priorities for further research in older, established medicines, as well as the use of polymer based systems and alternative dosage forms to improve acceptability and practicality of medicines by, for example, extending stability and providing taste-masking.

A particular area of interest is that of extemporaneous formulation – that is the process of compounding ingredients to prepare a medicine for an individual patient when no commercial forms are available – which is extremely prevalent for the paediatric and geriatric population, due to a severe lack of age-appropriate dosage forms available on the market.

In an attempt to tackle the major issues, our research involves engagement with representative groups of patients, carers and prescribers, whilst robust pharmaceutical characterisation of problematic formulations requiring investigation is also performed, as well as development of novel dosage forms. This is being conducted in order to both inform current practice and strive towards improved, age-appropriate formulations.

Current projects include the development of orally dissolving films and orally disintegrating tablets for paedatric applications, patient-centric dosage form design and elucidation of preferences for the elderly population, polymer based taste-masking platform technologies and novel uses of liposomes and carbon based systems for improved drug delivery.

Teaching Activity

Theme lead for Enteral Drug Delivery

Pharmaceutical calculations: basic maths, graphical methods, formulation calculations and statistics
Pharmaceutical formulation: routes of delivery, suspensions, emulsions, creams and ointments, paediatric drug delivery and microspheres

Qualifications

  • BSc in Chemistry and French, Aston University, 2003
  • PhD in Pharmaceutics / Drug Delivery, Aston University, 2007
  • Postgraduate Certificate in Professional Practice in Higher Education, Aston University, 2015

Employment

  • 2010 – date: Lecturer in Pharmaceutics / Drug Delivery, School of Life and Health Sciences, Aston University.
  • 2007 – 2010: Formulation Research Fellow, UK Medicines for Children Research Network, Aston University.

PhD Supervision

Self-funded PhD projects in Pharmaceutics / Drug Delivery will be available shortly for prospective students.  It is envisaged that fully funded studentships will also become available.

Membership of Professional Bodies

Member of the British Pharmacopoeia Expert Advisory Group on Unlicensed Medicines

Fellow of the Higher Education Academy

Member of the steering committee for the Age Related Medicines focus group of the Academy of Pharmaceutical Sciences

IAT accredited course – Named Animal Care and Welfare Officer (NACWO)

Journals:

Scientific Advisor to the Editors of the Journal of Pharmaceutical Sciences

Reviewer for International Journal of Pharmaceutics, Journal of Pharmaceutical Sciences, European Journal of Pharmaceutics and Biopharmaceutics, Journal of Liposome Research, Pharmazie, and Biomedical Microdevices

Research Interests

Email: d.j.kirby1@aston.ac.uk
Telephone: +44 (0)121 204 3006
Room: MB 434e

Keywords

  • RS Pharmacy and materia medica
  • Pharmaceutics
  • Formulation
  • Patient-centric dosage form design
  • Age appropriate formulation
  • Particulate drug delivery systems

Fingerprint Dive into the research topics where Daniel Kirby is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 8 Similar Profiles
Liposomes Medicine & Life Sciences
Vaccines Medicine & Life Sciences
Trehalose Medicine & Life Sciences
Antigens Medicine & Life Sciences
Microspheres Medicine & Life Sciences
Pharmaceutical Preparations Medicine & Life Sciences
Tablets Medicine & Life Sciences
Subunit Vaccines Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2003 2019

Conceptualisation, Development, Fabrication and In Vivo Validation of a Novel Disintegration Tester for Orally Disintegrating Tablets

Koner, J., Rajabi-Siahboomi, A., Missaghi, S., Kirby, D. J., Perrie, Y., Ahmed, J. & Mohammed, A., 28 Aug 2019, In : Scientific Reports. 9, 12467 .

Research output: Contribution to journalArticle

Open Access
File
Tablets
Pharmacopoeias
Mouth
Hockey
Dosage Forms

Liposomes: a promising carrier for respiratory syncytial virus therapeutics

Joshi, S., Bawage, S., Tiwari, P., Kirby, D., Perrie, Y., Dennis, V. & Singh, S. R., 7 Aug 2019, In : Expert Opinion on Drug Delivery. 16, 9, p. 969-980 12 p.

Research output: Contribution to journalReview article

Respiratory Syncytial Viruses
Liposomes
Human respiratory syncytial virus
Therapeutics
Respiratory Syncytial Virus Infections

Anti-RSV Peptide-Loaded Liposomes for the Inhibition of Respiratory Syncytial Virus

Joshi, S., Chaudhari, A. A., Dennis, V., Kirby, D. J., Perrie, Y. & Singh, S. R., 9 May 2018, In : Bioengineering (Basel, Switzerland). 5, 2, 37.

Research output: Contribution to journalArticle

Open Access
File
Liposomes
Viruses
Peptides
Fusion reactions

Activated carbon as a carrier for amorphous drug delivery: effect of drug characteristics and carrier wettability

Miriyala, N., Ouyang, D., Perrie, Y., Lowry, D. & Kirby, D. J., 1 Mar 2017, In : European Journal of Pharmaceutics and Biopharmaceutics. 115, p. 197–205 9 p.

Research output: Contribution to journalArticle

Open Access
File
Wettability
Drug Carriers
Carbon
Pharmaceutical Preparations
Caco-2 Cells

Environmental scanning electron microscope imaging of vesicle systems

Perrie, Y., Ali, H., Kirby, D. J., Mohammed, A. U. R., McNeil, S. E. & Vangala, A., 2017, Liposomes: methods and protocols. d'Souza, G. G. M. (ed.). New York (US): Springer, p. 131-143 13 p. (Methods in Molecular Biology; vol. 1522).

Research output: Chapter in Book/Report/Conference proceedingChapter

Liposomes
Electrons
Electron Scanning Microscopy
Freeze Fracturing
Transmission Electron Microscopy

Thesis

Design and characterisation of orally dissolving films as a potential new dosage form for paediatrics

Author: Pham, T., 15 Sep 2017

Supervisor: Ouyang, D. (Supervisor) & Kirby, D. J. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

File

Formulation and characterisation of an effective particulate delivery vehicle for the novel sub-unit vaccine antigen, Ag85B-ESAT-6

Author: Kirby, D. J., Jul 2007

Supervisor: Perrie, Y. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

File

Liposomes: a multifaceted delivery system

Author: Joshi, S., 23 Jun 2017

Supervisor: Kirby, D. J. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

File

Porous carbon carriers for amorphous drug delivery

Author: Miriyala, N., 5 Jan 2018

Supervisor: Kirby, D. J. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

File

Activities 2012 2012

  • 1 Participation in conference

UKICRS 2012 Symposium - Drug Delivery: through the ages

Daniel Kirby (Participant)
2 May 2012

Activity: Participating in or organising an event typesParticipation in conference