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Personal profile

General

I joined Aston University in June 2010 as Lecturer in Pharmacokinetics following over 3 years of extensive pharmacokinetics training with the world-renowned Centre for Applied Pharmacokinetics Research as a post-doctorate research associate, within the School of Pharmacy at the University of Manchester.

I have a broad background and interest in applying the principles of clinical pharmacokinetics to challenging pre-clinical and clinical scenarios in the context of medicines optimisation.  As a pharmacokineticist and practicing pharmacist, I have a singular vision of developing tools and approaches which provide clear end-user/clinical benefits.  This approach has driven successes in developing research tools to predict oral drug absorption and central nervous system drug biodistribution in addition to medicines optimisation for a range of disease conditions (e.g. tropical disease, cardiovascular disease, drug abuse).  

Research Interests

The goal of my research group is to provide guidance in the development, evaluation and implementation of approaches for predicting and improving clinical pharmacokinetics to optimise dosing through medicines optimisation.


Research strands actively pursued within this group are translational and include the techniques of:

  • Whole Body Physiologically-Based Pharmacokinetic Modelling
  • Population pharmacokinetics

 

Which are widely applied to a variety of research interests, which include:

  • Medicines optimisation
  • Deprescribing
  • Mental health
  • Opioid abuse
  • Tropical disease


Collaborative research is welcome and encouraged, please contact me for more details

 

Teaching Activity

PH1403: Mathematics.
PH2503: Stability kinetics.
PH3603 (module coordinator): Pharmacokinetics, biopharmaceutics.

I am the module coordinator and teach  3rd year MPharm Pharmaceutics module PH3CT1 (Pharmacokinetics, Biopharmaceutics) and MSc. Drug Delivery/Pharmaceutical Sciences module BI4010.  I also teach Stability Kinetics (PH2CT2) and mathematics (PH1CT1) throughout the MPharm course.

Qualifications

  • MPharm (Masters in Pharmacy) 2(i), School of Pharmacy, University of Manchester, 2001
  • PhD (Pharmacology, Molecular Biology and Pharmacokinetics), School of Pharmacy, University of Manchester, 2005  

Employment

  • 2010-date:  Lecturer in Pharmacokinetics, School of Pharmacy, Aston University
  • 2005-2009: Post-Doctorate Research Associate (Pharmacokinetics/Pharmacometrics), Centre for Applied Pharmacokinetics Research (CAPKR), School of Pharmacy, University of Manchester, United Kingdom
  • 2002-date: Locum pharmacist for national pharmacy chains 
  • 2001-2002: Pre-registration pharmacist, Superdrug Pharmacy, Wolverhampton, United Kingdom  

Membership of Professional Bodies

  • Royal Pharmaceutical Society of Great Britain
  • International Society for the Study of Xenobiotics
  • Academy of Pharmaceutical Sciences Great Britain (APSGB)
  • United Kindgom and Ireland Controlled Release Society (UKICRS)

Contact Details

Room: Main Building-434C
Email: r.k.s.badhan@aston.ac.uk 
Telephone:
 0121 204 3288

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Research Output

A dynamic perfusion based blood-brain barrier model for cytotoxicity testing and drug permeation

Elbakary, B. & Badhan, R. K. S., 2 Mar 2020, In : Scientific Reports. 10, 1, 3788.

Research output: Contribution to journalArticle

Open Access
File
  • High-throughput screening of excipients with a biological effect: a kinetic study on the effects of surfactants on efflux-mediated transport

    Pollard, J., Rajabi-siahboomi, A., Badhan, R. K. S., Mohammed, A. R. & Perrie, Y., 1 Jun 2019, In : Journal of Pharmacy and Pharmacology. 71, 6, p. 889-897 9 p.

    Research output: Contribution to journalArticle

    Open Access
    File
  • Intracellular uptake of EGCG-loaded deformable controlled release liposomes for skin cancer

    Marwah, M., Perrie, Y., Badhan, R. K. S. & Lowry, D., 9 May 2019, In : Journal of Liposome Research. 14 p.

    Research output: Contribution to journalArticle

  • The optimization of methadone dosing whilst treating with rifampicin: A pharmacokinetic modeling study

    Badhan, R. K. S., Gittins, R. & Al Zabit, D., 1 Jul 2019, In : Drug and Alcohol Dependence. 200, p. 168-180 13 p.

    Research output: Contribution to journalArticle

  • Thesis

    Aquasomes: multilayered nanoparticular drug delivery systems

    Author: Udo-Chijioke, O., 2016

    Supervisor: Badhan, R. K. (Supervisor) & Lowry, D. (Supervisor)

    Student thesis: Doctoral ThesisDoctor of Philosophy

    File

    Development of novel delivery systems for nose-to-brain drug delivery

    Author: Lungare, S., 31 May 2017

    Supervisor: Badhan, R. K. (Supervisor)

    Student thesis: Doctoral ThesisDoctor of Philosophy

    File

    Orally disintegrating tablets: formulation development, novel engineering solutions and fixed dose combinations

    Author: Dennison, T., 14 Mar 2017

    Supervisor: Mohammed, A. (Supervisor) & Badhan, R. K. (Supervisor)

    Student thesis: Doctoral ThesisDoctor of Philosophy

    File

    Physiologically based pharmacokinetic modelling of antimalarial agents

    Author: Olafuyi, O., 16 Jul 2019

    Supervisor: Badhan, R. K. S. (Supervisor) & Coleman, M. (Supervisor)

    Student thesis: Doctoral ThesisDoctor of Philosophy

    File

    Phytochemical mediated modulation of breast cancer resistance protein at the blood brain barrier and blood cerebrospinal fluid barrier

    Author: Kaur, M., 13 Jun 2016

    Supervisor: Badhan, R. K. (Supervisor)

    Student thesis: Doctoral ThesisDoctor of Philosophy

    File