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Personal profile

Research Interests

Electrophysiological studies on neurones of the entorhinal cortex (EC) and hippocampus.

The role of glutamate and GABA receptors in epilepsy in the brain; the role of homeodynamic synaptic scaling in epileptogenesis in the temporal lobe. Autoimmune epilepsies, psychosis and neuronal network dynamics; the relationaship between epilepsy and affective disorders. The role of cannabinoids in epilepsy tresatment (collabration with GW Pharma). The role of primary motor cortex in epilepsy and Parkinson’s disease (in collaboration with Dr. Stuart Greenhill)

The temporal lobe is a brain region which is especially prone to epilepsy. My research focuses on how epilepsy is established, and how dynamic changes in receptor expression and function leads to changes in neronal network behaviour that may underlie epileptic seizures. I am interested too, in how neuronal network dynamics alter in schizophrenia, and how epilepsy and schizophrenia relate to each other in terms of pathological network fnction.

Teaching Activity

PH2501: Antidysrhythmic drugs.
PH3601: Glutamate, drug abuse, epilepsy, general aAnaesthetics.
Course Director, BSc Neuroscience

NE2001: Key Skills n Neurosciences

NE1008: Practical studies in Neurosciences 1

NE2008: Practical studies in Neurosciences 2

NE2003: Systems Neuroscience

NE1009: PIlls and Poisons, toxins and their use in Neuroscience research

NE3010: Psychosis and schizophrenia

NE3008: Epilepsy and neuronal networks

Employment

  • 1998–2002 Post-doctoral researcher, University of Bristol.
  • 1995–1998 Postdoctoral fellow University of Montreal, Canada.
  • 1994–1995 Postdoctoral Fellow University of Southampton.
  • 1991–1994 PhD University of Southampton

Contact Details

Email: g.l.woodhall@aston.ac.uk
Telephone: +44 (0) 121 204 3995

Education/Academic qualification

PhD, University of Southampton

External positions

External Examiner, University of Southampton

1 Mar 201928 Feb 2022

External Examiner, University of Bath

1 Mar 201515 Jun 2019

EXternal Examiner

1 Mar 201315 Jun 2016

Fingerprint Dive into the research topics where Gavin L Woodhall is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 6 Similar Profiles
Entorhinal Cortex Medicine & Life Sciences
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gamma-Aminobutyric Acid Medicine & Life Sciences
Metabotropic Glutamate Receptors Medicine & Life Sciences
Glutamic Acid Medicine & Life Sciences
Motor Cortex Medicine & Life Sciences
Interneurons Medicine & Life Sciences
Autoreceptors Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 1997 2019

Changes in excitatory and inhibitory receptor expression and network activity during induction and establishment of epilepsy in the rat Reduced Intensity Status Epilepticus (RISE) model

Needs, H. I., Henley, B. S., Cavallo, D., Gurung, S., Modebadze, T., Woodhall, G. & Henley, J. M., 1 Nov 2019, In : Neuropharmacology. 158, 107728.

Research output: Contribution to journalArticle

Open Access
File
Status Epilepticus
Epilepsy
Seizures
Hippocampus
Temporal Lobe

Dopamine acting at D1-like, D2-like and α1-adrenergic receptors differentially modulates theta and gamma oscillatory activity in primary motor cortex

Özkan, M., Johnson, N. W., Sehirli, U. S., Woodhall, G. L. & Stanford, I. M., 21 Jul 2017, In : PLoS ONE. 12, 7, 15 p., e0181633.

Research output: Contribution to journalArticle

Open Access
File
Motor Cortex
adrenergic receptors
dopamine
Adrenergic Receptors
Dopamine

Phase-amplitude coupled persistent theta and gamma oscillations in rat primary motor cortex in vitro

Johnson, N. W., Özkan, M., Burgess, A. P., Prokic, E. J., Wafford, K. A., O'Neill, M. J., Greenhill, S. D., Stanford, I. M. & Woodhall, G. L., Jun 2017, In : Neuropharmacology. 119, p. 141–156 16 p.

Research output: Contribution to journalArticle

Open Access
File
Motor Cortex
Picrotoxin
Carbenoxolone
GABA-A Receptor Antagonists
Excitatory Amino Acid Antagonists

A low mortality, high morbidity Reduced Intensity Status Epilepticus (RISE) model of epilepsy and epileptogenesis in the rat

Modebadze, T., Morgan, N. H., Pérès, I. A. A., Hadid, R. D., Amada, N., Hill, C., Williams, C., Stanford, I. M., Morris, C. M., Jones, R. S. G., Whalley, B. J. & Woodhall, G. L., 24 Feb 2016, In : PLoS ONE. 11, 2, 19 p., e0147265.

Research output: Contribution to journalArticle

Open Access
File
epilepsy
Status Epilepticus
morbidity
seizures
Rats

Human brain slices for epilepsy research: pitfalls, solutions and future challenges

Jones, R. S. G., Brito da Silva, A., Whittaker, R. G., Woodhall, G. L. & Cunningham, M. O., 15 Feb 2016, In : Journal of Neuroscience Methods. 260, p. 221-232 12 p.

Research output: Contribution to journalArticle

Open Access
File
Epilepsy
Brain
Research
Culture Techniques
Neurosurgical Procedures

Thesis

A model of delta frequency neuronal network activity and theta-gamma interactions in rat sensorimotor cortex in vitro

Author: Kalyanapu, S. S., 2017

Supervisor: Stanford, I. M. (Supervisor) & Woodhall, G. L. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

File

Beta frequency neuronal network activity in the primary motor cortex

Author: Yamawaki, N., Jan 2009

Supervisor: Stanford, I. M. (Supervisor) & Woodhall, G. L. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

File

Characterising the anti-convulsant effects of CBD and CBDV on layer II of the medial entorhinal cortex of rat and human brain tissue in vitro 

Author: Henley, B., 22 Oct 2018

Supervisor: Woodhall, G. L. (Supervisor) & Stanford, I. M. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

File

Effect of dopamine on synchronous neuronal oscillations in the globus pallidus-subthalamic nucleus network

Author: Loucif, A. J., 2006

Supervisor: Woodhall, G. L. (Supervisor) & Martin, I. L. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

File