An astrocyte bridge from synapse to blood flow

Rheinallt Parri, Vincenzo Crunelli

Research output: Contribution to journalLetter, comment/opinion or interviewpeer-review


Neural activity locally Increases cerebral blood flow to deliver oxygen to working neurons. A new paper shows that astrocytes can detect activity at glutamatergic synapses via calcium changes In astrocytic endfeet and directly couple It to blood flow in vitro and In vivo.
Original languageEnglish
Pages (from-to)5-6
Number of pages2
JournalNature Neuroscience
Issue number1
Publication statusPublished - 2003


  • Animals
  • Astrocytes
  • Brain
  • Cerebrovascular Circulation
  • Energy Metabolism
  • Glutamic Acid
  • Humans
  • Microcirculation
  • Presynaptic Terminals
  • Signal Transduction
  • Synaptic Transmission
  • Vasodilation


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