Impact of physical activity category on incidence of cardiovascular disease: Results from the 10-year follow-up of the ATTICA Study (2002–2012)

Konstantinos D. Tambalis, Demosthenes B. Panagiotakos*, Ekavi N. Georgousopoulou, Duane D. Mellor, Christina Chrysohoou, Georgia Maria Kouli, Dimitrios Tousoulis, Christodoulos Stefanadis, Christos Pitsavos

*Corresponding author for this work

Research output: Contribution to journalArticle

Abstract

The aim of the study was to examine the effects of physical activity (PA) level on 10-year cardiovascular disease (CVD) incidence, taking into consideration several clinical and lifestyle risk factors along with the potential moderating role of gender. An analysis was undertaken on data from the ATTICA prospective cohort study (10-year follow-up, 2002–2012), which followed a Greek adult population (aged 18–89 years). A total n = 317 of fatal and nonfatal CVD events occurred among the 2020 participants. After adjusting for the lifestyle and clinical risk factors as potential confounders, odds ratio (ORs) of CVD risk of individuals who reported being sufficiently active and highly active were decreased by 58% (95% CI: 0.30, 0.58) and 70% (95% CI: 0.15, 0.56), when compared to those who were inactive/insufficiently active, respectively. Men had nearly two-fold increase in risk of CVD (95% CI: 1.62, 2.18) versus women. Stratified analysis by gender, revealed that sufficiently active men, had 52% (95% CI: 0.24, 0.97) reduced risk of CVD incidence when compared to inactive males, while, for women, the role of PA lost significance following adjusting for lifestyle factors. The current data suggests a beneficial effect of even moderate physical activity levels on 10-year incidence of CVD, reinforcing the importance of physically activity, especially for men.

Original languageEnglish
Pages (from-to)27-32
Number of pages6
JournalPreventive Medicine
Volume93
Early online date20 Sep 2016
DOIs
Publication statusPublished - 1 Dec 2016

Bibliographical note

© 2016, Elsevier. Licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International http://creativecommons.org/licenses/by-nc-nd/4.0/

Keywords

  • CVD
  • Physical activity level
  • Prospective study

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