TY - JOUR
T1 - Impact of physical activity category on incidence of cardiovascular disease
T2 - Results from the 10-year follow-up of the ATTICA Study (2002–2012)
AU - Tambalis, Konstantinos D.
AU - Panagiotakos, Demosthenes B.
AU - Georgousopoulou, Ekavi N.
AU - Mellor, Duane D.
AU - Chrysohoou, Christina
AU - Kouli, Georgia Maria
AU - Tousoulis, Dimitrios
AU - Stefanadis, Christodoulos
AU - Pitsavos, Christos
N1 - © 2016, Elsevier. Licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International http://creativecommons.org/licenses/by-nc-nd/4.0/
PY - 2016/12/1
Y1 - 2016/12/1
N2 - The aim of the study was to examine the effects of physical activity (PA) level on 10-year cardiovascular disease (CVD) incidence, taking into consideration several clinical and lifestyle risk factors along with the potential moderating role of gender. An analysis was undertaken on data from the ATTICA prospective cohort study (10-year follow-up, 2002–2012), which followed a Greek adult population (aged 18–89 years). A total n = 317 of fatal and nonfatal CVD events occurred among the 2020 participants. After adjusting for the lifestyle and clinical risk factors as potential confounders, odds ratio (ORs) of CVD risk of individuals who reported being sufficiently active and highly active were decreased by 58% (95% CI: 0.30, 0.58) and 70% (95% CI: 0.15, 0.56), when compared to those who were inactive/insufficiently active, respectively. Men had nearly two-fold increase in risk of CVD (95% CI: 1.62, 2.18) versus women. Stratified analysis by gender, revealed that sufficiently active men, had 52% (95% CI: 0.24, 0.97) reduced risk of CVD incidence when compared to inactive males, while, for women, the role of PA lost significance following adjusting for lifestyle factors. The current data suggests a beneficial effect of even moderate physical activity levels on 10-year incidence of CVD, reinforcing the importance of physically activity, especially for men.
AB - The aim of the study was to examine the effects of physical activity (PA) level on 10-year cardiovascular disease (CVD) incidence, taking into consideration several clinical and lifestyle risk factors along with the potential moderating role of gender. An analysis was undertaken on data from the ATTICA prospective cohort study (10-year follow-up, 2002–2012), which followed a Greek adult population (aged 18–89 years). A total n = 317 of fatal and nonfatal CVD events occurred among the 2020 participants. After adjusting for the lifestyle and clinical risk factors as potential confounders, odds ratio (ORs) of CVD risk of individuals who reported being sufficiently active and highly active were decreased by 58% (95% CI: 0.30, 0.58) and 70% (95% CI: 0.15, 0.56), when compared to those who were inactive/insufficiently active, respectively. Men had nearly two-fold increase in risk of CVD (95% CI: 1.62, 2.18) versus women. Stratified analysis by gender, revealed that sufficiently active men, had 52% (95% CI: 0.24, 0.97) reduced risk of CVD incidence when compared to inactive males, while, for women, the role of PA lost significance following adjusting for lifestyle factors. The current data suggests a beneficial effect of even moderate physical activity levels on 10-year incidence of CVD, reinforcing the importance of physically activity, especially for men.
KW - CVD
KW - Physical activity level
KW - Prospective study
UR - http://www.scopus.com/inward/record.url?scp=84988476696&partnerID=8YFLogxK
UR - https://www.sciencedirect.com/science/article/pii/S009174351630281X?via%3Dihub
U2 - 10.1016/j.ypmed.2016.09.023
DO - 10.1016/j.ypmed.2016.09.023
M3 - Article
C2 - 27663426
AN - SCOPUS:84988476696
SN - 0091-7435
VL - 93
SP - 27
EP - 32
JO - Preventive Medicine
JF - Preventive Medicine
ER -