Nanoengineering heterogeneous catalysts for the selective hydrogenation of key agrochemical derivatives

Scott Board, Karen Wilson, Adam Lee

Research output: Contribution to journalMeeting abstract

Abstract

Rapidly rising world populations have sparked growing concerns over global food production to meet this increasing demand. Figures released by The World Bank suggest that a 50 % increase in worldwide cereal production is required by 2030. Primary amines are important intermediates in the synthesis of a wide variety of fine chemicals utilised within the agrochemical industry, and hence new 'greener' routes to their low cost manufacture from sustainable resources would permit significantly enhanced crop yields. Early synthetic pathways to primary amines employed stoichiometric (and often toxic) reagents via multi-step protocols, resulting in a large number of by-products and correspondingly high Environmental factors of 50-100 (compared with 1-5 for typical bulk chemicals syntheses). Alternative catalytic routes to primary amines have proven fruitful, however new issues relating to selectivity and deactivation have slowed commercialisation. The potential of heterogeneous catalysts for nitrile hydrogenation to amines has been demonstrated in a simplified reaction framework under benign conditions, but further work is required to improve the atom economy and energy efficiency through developing fundamental insight into nature of the active species and origin of on-stream deactivation. Supported palladium nanoparticles have been investigated for the hydrogenation of crotononitrile to butylamine (Figure 1) under favourable conditions, and the impact of reaction temperature, hydrogen pressure, support and loading upon activity and selectivity to C=C versus CºN activation assessed.
Original languageEnglish
Article number162-CATL
JournalAbstracts of Papers of the American Chemical Society
Volume248
Publication statusPublished - 10 Aug 2014
Event248th National Meeting of the American-Chemical-Society - San Francisco, CA, United States
Duration: 10 Aug 201414 Aug 2014

Fingerprint

Agrochemicals
Hydrogenation
Amines
Derivatives
Catalysts
Nitriles
Poisons
Palladium
Crops
Byproducts
Energy efficiency
Hydrogen
Thermodynamic properties
Chemical activation
Nanoparticles
Atoms
Costs
Industry
Temperature

Bibliographical note

248th National Meeting of the American-Chemical-Society (ACS), San Francisco, CA (US), 10-14 AUG, 2014.

Cite this

@article{72934d41a64a45b3bef217d006999df3,
title = "Nanoengineering heterogeneous catalysts for the selective hydrogenation of key agrochemical derivatives",
abstract = "Rapidly rising world populations have sparked growing concerns over global food production to meet this increasing demand. Figures released by The World Bank suggest that a 50 {\%} increase in worldwide cereal production is required by 2030. Primary amines are important intermediates in the synthesis of a wide variety of fine chemicals utilised within the agrochemical industry, and hence new 'greener' routes to their low cost manufacture from sustainable resources would permit significantly enhanced crop yields. Early synthetic pathways to primary amines employed stoichiometric (and often toxic) reagents via multi-step protocols, resulting in a large number of by-products and correspondingly high Environmental factors of 50-100 (compared with 1-5 for typical bulk chemicals syntheses). Alternative catalytic routes to primary amines have proven fruitful, however new issues relating to selectivity and deactivation have slowed commercialisation. The potential of heterogeneous catalysts for nitrile hydrogenation to amines has been demonstrated in a simplified reaction framework under benign conditions, but further work is required to improve the atom economy and energy efficiency through developing fundamental insight into nature of the active species and origin of on-stream deactivation. Supported palladium nanoparticles have been investigated for the hydrogenation of crotononitrile to butylamine (Figure 1) under favourable conditions, and the impact of reaction temperature, hydrogen pressure, support and loading upon activity and selectivity to C=C versus CºN activation assessed.",
author = "Scott Board and Karen Wilson and Adam Lee",
note = "248th National Meeting of the American-Chemical-Society (ACS), San Francisco, CA (US), 10-14 AUG, 2014.",
year = "2014",
month = "8",
day = "10",
language = "English",
volume = "248",
journal = "Abstracts of Papers of the American Chemical Society",
issn = "0065-7727",
publisher = "American Chemical Society",

}

Nanoengineering heterogeneous catalysts for the selective hydrogenation of key agrochemical derivatives. / Board, Scott; Wilson, Karen; Lee, Adam.

In: Abstracts of Papers of the American Chemical Society, Vol. 248, 162-CATL, 10.08.2014.

Research output: Contribution to journalMeeting abstract

TY - JOUR

T1 - Nanoengineering heterogeneous catalysts for the selective hydrogenation of key agrochemical derivatives

AU - Board, Scott

AU - Wilson, Karen

AU - Lee, Adam

N1 - 248th National Meeting of the American-Chemical-Society (ACS), San Francisco, CA (US), 10-14 AUG, 2014.

PY - 2014/8/10

Y1 - 2014/8/10

N2 - Rapidly rising world populations have sparked growing concerns over global food production to meet this increasing demand. Figures released by The World Bank suggest that a 50 % increase in worldwide cereal production is required by 2030. Primary amines are important intermediates in the synthesis of a wide variety of fine chemicals utilised within the agrochemical industry, and hence new 'greener' routes to their low cost manufacture from sustainable resources would permit significantly enhanced crop yields. Early synthetic pathways to primary amines employed stoichiometric (and often toxic) reagents via multi-step protocols, resulting in a large number of by-products and correspondingly high Environmental factors of 50-100 (compared with 1-5 for typical bulk chemicals syntheses). Alternative catalytic routes to primary amines have proven fruitful, however new issues relating to selectivity and deactivation have slowed commercialisation. The potential of heterogeneous catalysts for nitrile hydrogenation to amines has been demonstrated in a simplified reaction framework under benign conditions, but further work is required to improve the atom economy and energy efficiency through developing fundamental insight into nature of the active species and origin of on-stream deactivation. Supported palladium nanoparticles have been investigated for the hydrogenation of crotononitrile to butylamine (Figure 1) under favourable conditions, and the impact of reaction temperature, hydrogen pressure, support and loading upon activity and selectivity to C=C versus CºN activation assessed.

AB - Rapidly rising world populations have sparked growing concerns over global food production to meet this increasing demand. Figures released by The World Bank suggest that a 50 % increase in worldwide cereal production is required by 2030. Primary amines are important intermediates in the synthesis of a wide variety of fine chemicals utilised within the agrochemical industry, and hence new 'greener' routes to their low cost manufacture from sustainable resources would permit significantly enhanced crop yields. Early synthetic pathways to primary amines employed stoichiometric (and often toxic) reagents via multi-step protocols, resulting in a large number of by-products and correspondingly high Environmental factors of 50-100 (compared with 1-5 for typical bulk chemicals syntheses). Alternative catalytic routes to primary amines have proven fruitful, however new issues relating to selectivity and deactivation have slowed commercialisation. The potential of heterogeneous catalysts for nitrile hydrogenation to amines has been demonstrated in a simplified reaction framework under benign conditions, but further work is required to improve the atom economy and energy efficiency through developing fundamental insight into nature of the active species and origin of on-stream deactivation. Supported palladium nanoparticles have been investigated for the hydrogenation of crotononitrile to butylamine (Figure 1) under favourable conditions, and the impact of reaction temperature, hydrogen pressure, support and loading upon activity and selectivity to C=C versus CºN activation assessed.

M3 - Meeting abstract

VL - 248

JO - Abstracts of Papers of the American Chemical Society

JF - Abstracts of Papers of the American Chemical Society

SN - 0065-7727

M1 - 162-CATL

ER -