Pharmacological management of South Asians with type 2 diabetes: Consensus recommendations from the South Asian Health Foundation

Wasim Hanif; Sarah Ali; Srikanth Bellary; Vinod Patel; Azhar Farooqi; Muhammad Ali Karamat; Mujahid Saeed; Sobha Sivaprasad; Kiran Patel; Kamlesh Khunti

doi:10.1111/dme.14497

Pharmacological management of South Asians with type 2 diabetes: Consensus recommendations from the South Asian Health Foundation

Wasim Hanif, Sarah Ali, Srikanth Bellary, Vinod Patel, Azhar Farooqi, Muhammad Ali Karamat, Mujahid Saeed, Sobha Sivaprasad, Kiran Patel, Kamlesh Khunti

School of Biosciences

Research output: Contribution to journal › Review article › peer-review

Abstract

South Asians constitute approximately 1.6 billion people from the Indian subcontinent, comprising Afghanistan, Bangladesh, Bhutan, India, Maldives, Nepal, Pakistan and Sri Lanka; and make up the largest diaspora globally. Compared to the White European population, this group is at a higher risk of developing type 2 diabetes along with cardiovascular, renal and eye complications. Over the recent years, a number of new therapies for type 2 diabetes have become available for which cardiovascular outcome trials (CVOTs) have been published. The recent ADA/EASD consensus guidelines on diabetes, pre-diabetes and cardiovascular diseases’ offer a transitional shift in type 2 diabetes management. The new consensus recommendations are based on recent CVOTs, many of which had a representation of South Asian cohorts. In light of this new evidence, there is urgent need for an integrated, evidence-based, cost-effective and individualised approach specific for South Asians. This review takes into consideration the evidence from these CVOTs and provides best practice recommendations for optimal management of South Asian people with type 2 diabetes, alongside the previously published consensus report from South Asian Health Foundation in 2014 [1].

Original language	English
Article number	e14497
Journal	Diabetic medicine
Volume	38
Issue number	4
Early online date	10 Dec 2020
DOIs	https://doi.org/10.1111/dme.14497
Publication status	Published - Apr 2021

Bibliographical note

This is the peer reviewed version of the following article: Hanif, W., Ali, S., Bellary, S., Patel, V., Farooqi, A., Karamat, M.A., Saeed, M., Sivaprasad, S., Patel, K. and Khunti, K. (2020), Pharmacological management of South Asians with Type 2 Diabetes: Consensus Recommendations from the South Asian Health Foundation. Diabetic Medicine. Accepted Author Manuscript e14497., which has been published in final form at https://doi.org/10.1111/dme.14497. This article may be used for non-commercial purposes in accordance With Wiley Terms and Conditions for self-archiving.

Keywords

South Asians
cardiovascular disease
cardiovascular outcome trials
glucagon-like peptide-1 receptor agonists
practice guidelines
sodium-glucose transporter 2 inhibitors
type 2 diabetes

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10.1111/dme.14497Licence: CC BY-NC 3.0

Pharmacological management of South Asians with Type 2 Diabetes
This is the peer reviewed version of the following article: Hanif, W., Ali, S., Bellary, S., Patel, V., Farooqi, A., Karamat, M.A., Saeed, M., Sivaprasad, S., Patel, K. and Khunti, K. (2020), Pharmacological management of South Asians with Type 2 Diabetes: Consensus Recommendations from the South Asian Health Foundation. Diabetic Medicine. Accepted Author Manuscript e14497., which has been published in final form at https://doi.org/10.1111/dme.14497. This article may be used for non-commercial purposes in accordance With Wiley Terms and Conditions for self-archiving.
Accepted author manuscript, 15.6 MB

Cite this

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title = "Pharmacological management of South Asians with type 2 diabetes: Consensus recommendations from the South Asian Health Foundation",

abstract = "South Asians constitute approximately 1.6 billion people from the Indian subcontinent, comprising Afghanistan, Bangladesh, Bhutan, India, Maldives, Nepal, Pakistan and Sri Lanka; and make up the largest diaspora globally. Compared to the White European population, this group is at a higher risk of developing type 2 diabetes along with cardiovascular, renal and eye complications. Over the recent years, a number of new therapies for type 2 diabetes have become available for which cardiovascular outcome trials (CVOTs) have been published. The recent ADA/EASD consensus guidelines on diabetes, pre-diabetes and cardiovascular diseases{\textquoteright} offer a transitional shift in type 2 diabetes management. The new consensus recommendations are based on recent CVOTs, many of which had a representation of South Asian cohorts. In light of this new evidence, there is urgent need for an integrated, evidence-based, cost-effective and individualised approach specific for South Asians. This review takes into consideration the evidence from these CVOTs and provides best practice recommendations for optimal management of South Asian people with type 2 diabetes, alongside the previously published consensus report from South Asian Health Foundation in 2014 [1].",

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note = "This is the peer reviewed version of the following article: Hanif, W., Ali, S., Bellary, S., Patel, V., Farooqi, A., Karamat, M.A., Saeed, M., Sivaprasad, S., Patel, K. and Khunti, K. (2020), Pharmacological management of South Asians with Type 2 Diabetes: Consensus Recommendations from the South Asian Health Foundation. Diabetic Medicine. Accepted Author Manuscript e14497., which has been published in final form at https://doi.org/10.1111/dme.14497. This article may be used for non-commercial purposes in accordance With Wiley Terms and Conditions for self-archiving.",

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AU - Karamat, Muhammad Ali

AU - Saeed, Mujahid

AU - Sivaprasad, Sobha

AU - Patel, Kiran

AU - Khunti, Kamlesh

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Pharmacological management of South Asians with type 2 diabetes: Consensus recommendations from the South Asian Health Foundation

Abstract

Bibliographical note

Keywords

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