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Reaction profiling of a set of acrylamide-based human tissue transglutaminase inhibitors
Mahmood Jasim,
Daniel L Rathbone
Aston Pharmacy School
College of Health and Life Sciences
Research output
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Contribution to journal
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Article
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peer-review
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Chemistry
Acrylamide
51%
Crosslinking
45%
Cysteine
47%
Drug Target
62%
Glutamine
60%
Lysine
51%
Peptidomimetic
66%
Protein
22%
Reaction Activation Energy
37%
Sampling
45%
Simulation
34%
Transamidation
82%
Engineering & Materials Science
Activation energy
56%
Crosslinking
67%
Enzymes
62%
Molecules
53%
Neurodegenerative diseases
81%
Proteins
50%
Protonation
100%
Sampling
38%
Tissue
46%
Physics & Astronomy
activation energy
6%
approximation
9%
attack
19%
crosslinking
10%
cysteine
12%
drugs
9%
enzymes
9%
evaluation
5%
fibrosis
13%
glutamine
14%
inhibitors
63%
lysine
12%
Michael reaction
80%
molecules
4%
proteins
7%
sampling
7%
simulation
3%
warheads
27%