Photo of Tony Worthington

Tony Worthington, CSci FIBMS PhD FHEA. Health Professions Council (HCPC) registered: BS34219


    • United Kingdom


    Research output per year

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    Personal profile

    Research Interests

    My research interests lie within the field of Clinical Microbiology and Healthcare Associate Infections. Specific aeas of interest include:

    • Clostridium difficile and Staphylococcal Infections
    • Biofilms; infections associated with indwelling intravascular devices and prosthetic joints
    • Skin Antisepsis and Antimicrobials/AMR
    • Propionibacterium acnes and its association with chronic back pain and Modic 1 changes


    Teaching Activity

    My teaching activity is broad and includes: young learners, undergraduate level and PhD. I also undertake many public engagement activities to share my interests and knowledge wthin Microbiology.

    Taught Undergraduate Modules:

    Microbiology Level 4

    Microbiology Level 5

    Clinical Microbiology and Infectious Disease Level 6

    Funding Applications and Awards

    2005-2008 EPSRC CASE award (in collaboration with Insight Health Ltd): £100,000;
    studies on ehnanced skin antisepsis

    2007 -2010 EPSRC CASE award (in collaboration with Insight Health Ltd): £100,000;
    Formulation engineering stategies to enhance skin antisepsis and delivery of chlorhexidine

    2008-2011 EPSRC CASE award (in collaboration with Insight Health Ltd): £100,000;
    Germination formulatiion and the development of a smart polymer-based surface for elimination of C. difficile spores

    2009 -2012 KTP award (Department of Health/Insight Health Ltd): £164,000;
    Development of a germination solution for elimination of C. difficile spores

    2010-2013 EPSRC CASE award (in collaboration with Insight Health Ltd): £100,000;
    Development of a dual-action germinant-biocide for the elimination of C. diffficle
    and microorganisms commonly associated with healthcare associated infections

    2013-2016 ARCHA PhD Studentship (50% Industrial funding; Insight Health Ltd, UK): £75,000; Antimicrobial Bioglass

    2014-2017: Full-industrially funded PhD (Insight Health Ltd): £60,000. Antimicrobial efficacy of octenidine.

    2014: Students into Work Grant: The Society for Applied Microbiology, £2,500. This will support investigations into the association between Propionibacterium acnes and chronic lower back pain.


    2018-2021: Antimicrobial efficacy of novel XF compounds for the prevention, control and eradication of clinically and industrially relevant pathogens and biofilmsWorthington, T. & Lambert, P. £39,714.00, Destiny Pharma Plc


    2019-2021: Knowledge Transfer Partnership.  Development of an automated cleaning system (ACS) for flexible endoscopes to reduce residual microorganisms through the use of mesocrystals. £200,664;  Dr Andrew Sutherland and Dr Tony Worthington (Aston University), In collaboration with Partners Medical Ltd, Stoke on Trent)

    Contact Details

    Tel: +44 (0)121 204 3951      

    Room: MB438k

    Education/Academic qualification


    Award Date: 30 Oct 2000


    • L Education (General)
    • Undergraduate
    • PhD
    • Young Learners
    • RB Pathology
    • Clinical Microbiology
    • Antimicrobials
    • AMR
    • Biofilms
    • Clostridium difficile
    • Healthcare Associated Infections

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    Research Output

    A Revised Understanding of Clostridioides difficile Spore Germination

    Lawler, A., Lambert, P. & Worthington, T., 23 Apr 2020, In : Trends in Microbiology. 28, 9, p. 744-752 9 p.

    Research output: Contribution to journalReview article

    Open Access
  • Open Access
  • Open Access
  • The antimicrobial efficacy of hypoxia mimicking cobalt oxide doped phosphate-based glasses against clinically relevant Gram positive, Gram negative bacteria and a fungal strain

    Raja, F., Worthington, A., Isaacs, M., Forto Chungong, L., Burke, B., Addison, O. & Martin, R. A., 14 Jan 2019, In : ACS Biomaterials Science and Engineering. 5, 1, p. 283–293 11 p.

    Research output: Contribution to journalArticle

    Open Access
  • The antimicrobial efficacy of zinc doped phosphate-based glass for treating catheter associated urinary tract infections

    Raja, F. N. S., Worthington, T., Isaacs, M. A., Rana, K. S. & Martin, R. A., 1 Oct 2019, In : Materials Science and Engineering C. 103, 109868.

    Research output: Contribution to journalArticle

    Open Access
  • Thesis

    Serodiagnosis of staphylococcal sepsis

    Author: Worthington, T., 2000

    Student thesis: Doctoral ThesisDoctor of Philosophy



    • 1 Participation in conference
    • 1 Types of External academic engagement - Hosting an academic visitor

    22nd European Congress of Clinical Microbiology and Infectious Disease

    Tony Worthington (Participant)

    3 Apr 2012

    Activity: Participating in or organising an event typesParticipation in conference

    Student wishing to seek unpaid research experience – from India. Thirumulesh Enuganti working with Dr Hilton and Dr Worthington in lab 327 on microbiology research.

    Tony Worthington (Member)

    Oct 2011Apr 2012

    Activity: Other activity typesTypes of External academic engagement - Hosting an academic visitor