Tony Worthington, CSci FIBMS PhD FHEA. Health Professions Council (HCPC) registered: BS34219

Dr

  • United Kingdom

20012019
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Personal profile

Research Interests

My research interests lie within the field of Clinical Microbiology and Healthcare Associate Infections. Specific aeas of interest include:

  • Clostridium difficile and Staphylococcal Infections
  • Biofilms; infections associated with indwelling intravascular devices and prosthetic joints
  • Skin Antisepsis and Antimicrobials/AMR
  • Propionibacterium acnes and its association with chronic back pain and Modic 1 changes

Employment

Teaching Activity

My teaching activity is broad and includes: young learners, undergraduate level and PhD. I also undertake many public engagement activities to share my interests and knowledge wthin Microbiology.

Taught Undergraduate Modules:

Microbiology Level 4

Microbiology Level 5

Clinical Microbiology and Infectious Disease Level 6

Funding Applications and Awards

2005-2008 EPSRC CASE award (in collaboration with Insight Health Ltd): £100,000;
studies on ehnanced skin antisepsis

2007 -2010 EPSRC CASE award (in collaboration with Insight Health Ltd): £100,000;
Formulation engineering stategies to enhance skin antisepsis and delivery of chlorhexidine

2008-2011 EPSRC CASE award (in collaboration with Insight Health Ltd): £100,000;
Germination formulatiion and the development of a smart polymer-based surface for elimination of C. difficile spores

2009 -2012 KTP award (Department of Health/Insight Health Ltd): £164,000;
Development of a germination solution for elimination of C. difficile spores

2010-2013 EPSRC CASE award (in collaboration with Insight Health Ltd): £100,000;
Development of a dual-action germinant-biocide for the elimination of C. diffficle
and microorganisms commonly associated with healthcare associated infections

2013-2016 ARCHA PhD Studentship (50% Industrial funding; Insight Health Ltd, UK): £75,000; Antimicrobial Bioglass

2014-2017: Full-industrially funded PhD (Insight Health Ltd): £60,000. Antimicrobial efficacy of octenidine.

2014: Students into Work Grant: The Society for Applied Microbiology, £2,500. This will support investigations into the association between Propionibacterium acnes and chronic lower back pain.

 

2018-2021: Antimicrobial efficacy of novel XF compounds for the prevention, control and eradication of clinically and industrially relevant pathogens and biofilmsWorthington, T. & Lambert, P. £39,714.00, Destiny Pharma Plc

 

2019-2021: Knowledge Transfer Partnership.  Development of an automated cleaning system (ACS) for flexible endoscopes to reduce residual microorganisms through the use of mesocrystals. £200,664;  Dr Andrew Sutherland and Dr Tony Worthington (Aston University), In collaboration with Partners Medical Ltd, Stoke on Trent)

Contact Details

Tel: +44 (0)121 204 3951      
email: T.Worthington@aston.ac.uk 

Room: MB438k

Education/Academic qualification

PhD

Keywords

  • L Education (General)
  • Undergraduate
  • PhD
  • Young Learners
  • RB Pathology
  • Clinical Microbiology
  • Antimicrobials
  • AMR
  • Biofilms
  • Clostridium difficile
  • Healthcare Associated Infections

Fingerprint Dive into the research topics where Tony Worthington is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 3 Similar Profiles
Coagulase Medicine & Life Sciences
Staphylococcus Medicine & Life Sciences
Clostridium difficile Medicine & Life Sciences
Catheter-Related Infections Medicine & Life Sciences
Central Venous Catheters Medicine & Life Sciences
Sepsis Medicine & Life Sciences
Infection Medicine & Life Sciences
Eucalyptus Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2001 2019

The antimicrobial efficacy of hypoxia mimicking cobalt oxide doped phosphate-based glasses against clinically relevant Gram positive, Gram negative bacteria and a fungal strain

Raja, F., Worthington, A., Isaacs, M., Forto Chungong, L., Burke, B., Addison, O. & Martin, R. A., 14 Jan 2019, In : ACS Biomaterials Science and Engineering. 5, 1, p. 283–293 11 p.

Research output: Contribution to journalArticle

Open Access
File
Cobalt
Bacteria
Phosphates
Glass
Oxides

The antimicrobial efficacy of zinc doped phosphate-based glass for treating catheter associated urinary tract infections

Raja, F. N. S., Worthington, T., Isaacs, M. A., Rana, K. S. & Martin, R. A., 1 Oct 2019, In : Materials Science and Engineering C. 103, 109868.

Research output: Contribution to journalArticle

Catheters
infectious diseases
Zinc
phosphates
Phosphates
Public Opinion
Microbial Drug Resistance
Public Health
Learning
Pharmaceutical Preparations

Human adipose tissue-derived mesenchymal stem/stromal cells adhere to and inhibit the growth of Staphylococcus aureus and Pseudomonas aeruginosa

Wood, C. R., Al Dhahri, D., Al Delfi, I., Pickles, N. A., Sammons, R. L., Worthington, T., Wright, K. T. & Johnson, W. E. B., 1 Dec 2018, In : Journal of Medical Microbiology. 67, 12, p. 1789-1795 7 p.

Research output: Contribution to journalArticle

Mesenchymal Stromal Cells
Pseudomonas aeruginosa
Staphylococcus aureus
Adipose Tissue
Growth

Enhanced chlorhexidine skin penetration with 1,8-cineole

Casey, A. L., Karpanen, T. J., Conway, B. R., Worthington, T., Nightingale, P., Waters, R. & Elliott, T. S. J., 17 May 2017, In : BMC Infectious Diseases. 17, 1, 5 p., 350.

Research output: Contribution to journalArticle

Open Access
File
Chlorhexidine
Skin
2-Propanol
Surgical Wound Infection
Eucalyptus

Thesis

Development and characterisation of novel antimicrobial phosphate glasses for urinary tract infections

Author: Raja, F., 20 Feb 2018

Supervisor: Martin, R. A. (Supervisor) & Worthington, A. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

File

Epidemiology of hospital-acquired and community-onset meticillin-resistant Staphylococcus aureus

Author: Rollason, J., 2007

Supervisor: Hilton, A. C. (Supervisor), Lambert, P. A. (Supervisor) & Worthington, A. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

File

Evaluation of the antibacterial and cytotoxic activity of gallium doped bioactive glass versus 45S5 Bioglass®

Author: Begum, S., 2016

Supervisor: Martin, R. A. (Supervisor), Worthington, A. (Supervisor) & Johnson, W. E. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

File

Gram-positive infections in patients with end-stage renal disease

Author: Spare, M. K., Nov 2004

Supervisor: Elliott, T. S. (External person) (Supervisor), Lambert, P. A. (Supervisor) & Worthington, A. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

File

Phenotypic and genotypic characterisation of Clostridium Difficile

Author: Green, L. M., 16 Jun 2010

Supervisor: Worthington, A. (Supervisor) & Hilton, A. C. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

File

Activities 2011 2012

  • 1 Participation in conference
  • 1 Types of External academic engagement - Hosting an academic visitor

22nd European Congress of Clinical Microbiology and Infectious Disease

Tony Worthington (Participant)
3 Apr 2012

Activity: Participating in or organising an event typesParticipation in conference

Student wishing to seek unpaid research experience – from India. Thirumulesh Enuganti working with Dr Hilton and Dr Worthington in lab 327 on microbiology research.

Tony Worthington (Member)
Oct 2011Apr 2012

Activity: Other activity typesTypes of External academic engagement - Hosting an academic visitor