Photo of Tony Worthington

Tony Worthington, CSci FIBMS PhD FHEA. Health Professions Council (HCPC) registered: BS34219

Dr

    • United Kingdom

    20012019
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    Personal profile

    Research Interests

    My research interests lie within the field of Clinical Microbiology and Healthcare Associate Infections. Specific aeas of interest include:

    • Clostridium difficile and Staphylococcal Infections
    • Biofilms; infections associated with indwelling intravascular devices and prosthetic joints
    • Skin Antisepsis and Antimicrobials/AMR
    • Propionibacterium acnes and its association with chronic back pain and Modic 1 changes

    Employment

    Teaching Activity

    My teaching activity is broad and includes: young learners, undergraduate level and PhD. I also undertake many public engagement activities to share my interests and knowledge wthin Microbiology.

    Taught Undergraduate Modules:

    Microbiology Level 4

    Microbiology Level 5

    Clinical Microbiology and Infectious Disease Level 6

    Funding Applications and Awards

    2005-2008 EPSRC CASE award (in collaboration with Insight Health Ltd): £100,000;
    studies on ehnanced skin antisepsis

    2007 -2010 EPSRC CASE award (in collaboration with Insight Health Ltd): £100,000;
    Formulation engineering stategies to enhance skin antisepsis and delivery of chlorhexidine

    2008-2011 EPSRC CASE award (in collaboration with Insight Health Ltd): £100,000;
    Germination formulatiion and the development of a smart polymer-based surface for elimination of C. difficile spores

    2009 -2012 KTP award (Department of Health/Insight Health Ltd): £164,000;
    Development of a germination solution for elimination of C. difficile spores

    2010-2013 EPSRC CASE award (in collaboration with Insight Health Ltd): £100,000;
    Development of a dual-action germinant-biocide for the elimination of C. diffficle
    and microorganisms commonly associated with healthcare associated infections

    2013-2016 ARCHA PhD Studentship (50% Industrial funding; Insight Health Ltd, UK): £75,000; Antimicrobial Bioglass

    2014-2017: Full-industrially funded PhD (Insight Health Ltd): £60,000. Antimicrobial efficacy of octenidine.

    2014: Students into Work Grant: The Society for Applied Microbiology, £2,500. This will support investigations into the association between Propionibacterium acnes and chronic lower back pain.

     

    2018-2021: Antimicrobial efficacy of novel XF compounds for the prevention, control and eradication of clinically and industrially relevant pathogens and biofilmsWorthington, T. & Lambert, P. £39,714.00, Destiny Pharma Plc

     

    2019-2021: Knowledge Transfer Partnership.  Development of an automated cleaning system (ACS) for flexible endoscopes to reduce residual microorganisms through the use of mesocrystals. £200,664;  Dr Andrew Sutherland and Dr Tony Worthington (Aston University), In collaboration with Partners Medical Ltd, Stoke on Trent)

    Contact Details

    Tel: +44 (0)121 204 3951      
    email: T.Worthington@aston.ac.uk 

    Room: MB438k

    Education/Academic qualification

    PhD

    Keywords

    • L Education (General)
    • Undergraduate
    • PhD
    • Young Learners
    • RB Pathology
    • Clinical Microbiology
    • Antimicrobials
    • AMR
    • Biofilms
    • Clostridium difficile
    • Healthcare Associated Infections

    Fingerprint Dive into the research topics where Tony Worthington is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

    • 3 Similar Profiles
    Coagulase Medicine & Life Sciences
    Staphylococcus Medicine & Life Sciences
    Clostridium difficile Medicine & Life Sciences
    Catheter-Related Infections Medicine & Life Sciences
    Central Venous Catheters Medicine & Life Sciences
    Sepsis Medicine & Life Sciences
    Infection Medicine & Life Sciences
    Eucalyptus Medicine & Life Sciences

    Network Recent external collaboration on country level. Dive into details by clicking on the dots.

    Research Output 2001 2019

    The antimicrobial efficacy of hypoxia mimicking cobalt oxide doped phosphate-based glasses against clinically relevant Gram positive, Gram negative bacteria and a fungal strain

    Raja, F., Worthington, A., Isaacs, M., Forto Chungong, L., Burke, B., Addison, O. & Martin, R. A., 14 Jan 2019, In : ACS Biomaterials Science and Engineering. 5, 1, p. 283–293 11 p.

    Research output: Contribution to journalArticle

    Open Access
    File
    Cobalt
    Bacteria
    Phosphates
    Glass
    Oxides

    The antimicrobial efficacy of zinc doped phosphate-based glass for treating catheter associated urinary tract infections

    Raja, F. N. S., Worthington, T., Isaacs, M. A., Rana, K. S. & Martin, R. A., 1 Oct 2019, In : Materials Science and Engineering C. 103, 109868.

    Research output: Contribution to journalArticle

    Catheters
    infectious diseases
    Zinc
    phosphates
    Phosphates
    Public Opinion
    Microbial Drug Resistance
    Public Health
    Learning
    Pharmaceutical Preparations

    Human adipose tissue-derived mesenchymal stem/stromal cells adhere to and inhibit the growth of Staphylococcus aureus and Pseudomonas aeruginosa

    Wood, C. R., Al Dhahri, D., Al Delfi, I., Pickles, N. A., Sammons, R. L., Worthington, T., Wright, K. T. & Johnson, W. E. B., 1 Dec 2018, In : Journal of Medical Microbiology. 67, 12, p. 1789-1795 7 p.

    Research output: Contribution to journalArticle

    Mesenchymal Stromal Cells
    Pseudomonas aeruginosa
    Staphylococcus aureus
    Adipose Tissue
    Growth

    Enhanced chlorhexidine skin penetration with 1,8-cineole

    Casey, A. L., Karpanen, T. J., Conway, B. R., Worthington, T., Nightingale, P., Waters, R. & Elliott, T. S. J., 17 May 2017, In : BMC Infectious Diseases. 17, 1, 5 p., 350.

    Research output: Contribution to journalArticle

    Open Access
    File
    Chlorhexidine
    Skin
    2-Propanol
    Surgical Wound Infection
    Eucalyptus

    Thesis

    Development and characterisation of novel antimicrobial phosphate glasses for urinary tract infections

    Author: Raja, F., 20 Feb 2018

    Supervisor: Martin, R. A. (Supervisor) & Worthington, A. (Supervisor)

    Student thesis: Doctoral ThesisDoctor of Philosophy

    File

    Epidemiology of hospital-acquired and community-onset meticillin-resistant Staphylococcus aureus

    Author: Rollason, J., 2007

    Supervisor: Hilton, A. C. (Supervisor), Lambert, P. A. (Supervisor) & Worthington, A. (Supervisor)

    Student thesis: Doctoral ThesisDoctor of Philosophy

    File

    Evaluation of the antibacterial and cytotoxic activity of gallium doped bioactive glass versus 45S5 Bioglass®

    Author: Begum, S., 2016

    Supervisor: Martin, R. A. (Supervisor), Worthington, A. (Supervisor) & Johnson, W. E. (Supervisor)

    Student thesis: Doctoral ThesisDoctor of Philosophy

    File

    Gram-positive infections in patients with end-stage renal disease

    Author: Spare, M. K., Nov 2004

    Supervisor: Elliott, T. S. (External person) (Supervisor), Lambert, P. A. (Supervisor) & Worthington, A. (Supervisor)

    Student thesis: Doctoral ThesisDoctor of Philosophy

    File

    Phenotypic and genotypic characterisation of Clostridium Difficile

    Author: Green, L. M., 16 Jun 2010

    Supervisor: Worthington, A. (Supervisor) & Hilton, A. C. (Supervisor)

    Student thesis: Doctoral ThesisDoctor of Philosophy

    File

    Activities 2011 2012

    • 1 Participation in conference
    • 1 Types of External academic engagement - Hosting an academic visitor

    22nd European Congress of Clinical Microbiology and Infectious Disease

    Tony Worthington (Participant)
    3 Apr 2012

    Activity: Participating in or organising an event typesParticipation in conference

    Student wishing to seek unpaid research experience – from India. Thirumulesh Enuganti working with Dr Hilton and Dr Worthington in lab 327 on microbiology research.

    Tony Worthington (Member)
    Oct 2011Apr 2012

    Activity: Other activity typesTypes of External academic engagement - Hosting an academic visitor