Professor Andrew Pitt

Andrew Pitt

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Research interests

My research has always been about understanding how biology works at the molecular level, using a multidisciplinary approach combining chemistry, biology, physics and engineering. We are developing techniques and technologies and applying them to help to understand complex biological problems, but to be effective this has to be done collaboration with many other talented research groups.  Many of the techniques and technologies we are developing also have a much broader applications, and we have research in many areas including drug discovery and analysis, chemical biology, biomarker discovery, biotechnology, biocatalysis, and systems and synthetic biology. One of our aims is to generate a better understanding, diagnosis, stratification, and treatment of disease, from identifying new targets for drugs, through to monitoring the therapeutic effect of drugs in the clinic.
At the cellular level we are interested in how the complex pathways involved in intracellular signalling are regulated, the role of redox chemistry in signalling and cellular damage, and understanding the molecular targets of drugs.

To see how I got into this and some of the research that I have been involved in along the way, you can watch my Inaugural Lecture on YouTube.

 

I am professor of Pharmaceutical Chemistry and Chemical Biology, but what are these?

  • Pharmaceutical chemistry is the process of making a new drugs, including their design, synthesis, and optimization of the drug molecules.
  • Chemical biology is the application of chemistry, including the use of chemical compounds and chemical tools and technologies, to study and manipulate biology.

Teaching Activity

MPharm Programme

PH3602: Antimicrobial agents and anticancer agents
PH3605: Medicinal chemistry – drugs from natural products and modern approaches to target discovery

Pharmacy Postgraduate Programme

PHM009: Antimicrobial agents and anticancer agents

Membership of Professional Bodies

  • Fellow of the Royal Society of Chemistry

  • Fellow of the Royal Society of Biology

  • Council member of the Chemistry Biology Interface Division of the Royal Society of Chemistry
  • Treasurer and past President of the British Society for Proteome Research (BSPR)

  • Member of the Executive Council of the European Proteomics Association and Chair of the Journals committee

  • Member of The Biochemical Society

Qualifications

BSc Chemistry (1st Class Honours), University of Bristol

DPhil Bioorganic Chemistry, University of Oxford

Employment

2019 -                 Assocoate Head of Pharmacy (Research), Aston University

2017-2018           Associate Dean for Research, Life and Health Sciences, Aston University

2012 -                 Professor of Pharmaceutical Chemistry and Chemical Biology, Aston University

2009 - 2011         Reader, Division of Integrative and Systems Biology, Institute of Biomedical and Life Sciences                              

2005 - 2011         Director, RASOR Interdisciplinary Research Collaboration in Proteomic Technologies                            
2005 - 2011         Director, Doctoral Training Centre in Proteomics

2005 - 2011         Director, Sir Henry Wellcome Functional Genomics Facility

2005 - 2009         Senior Lecturer in Proteomics, Division of Integrative and Systems Biology, Institute of Biomedical and Life Sciences                            

2002 - 2005         Deputy Director and Head of Proteomics, SHWFGF, University of Glasgow

1993 - 2002         Lecturer, Department of Pure and Applied Chemistry, University of Strathclyde.

1990 - 1993         Research Fellow, St. Catharine's College, Cambridge.

1989 - 1992         Schering Fellow in Bioorganic Chemistry, Department of Chemistry, University of Cambridge  

1988 - 1989         Research Assistant, Oxford University.

 

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Clinical and Systems Neuroscience

Organisational unit: School

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