Structure and regulation of type 2 transglutaminase in relation to its physiological functions and pathological roles

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Abstract

This chapter contains sections titled:
Introduction
Structure and Regulation
Physiologic Functions of TG2
Disruption of TG2 Functions in Pathologic Conditions
Perspectives for Pharmacologic Interventions
Concluding Comments
Acknowledgements
References

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Publication date16 Dec 2011
Publication titleAdvances in enzymology : and related areas of molecular biology
EditorsEric J. Toone
Place of PublicationHoboken, NJ (US)
PublisherWiley
Pages1-46
Number of pages46
Volume78
ISBN (Electronic)978-1-118-10577-1
ISBN (Print)978-1-118-01428-8, 1-118-01428-6
Original languageEnglish

    Keywords

  • animals, catalysis, disease, GTP-binding proteins, enzymologic gene expression regulation, humans, biological models, molecular models, molecular targeted therapy, structure-activity relationship, tissue distribution, transglutaminases

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