Photo of Shakil Ahmad
20002021

Research output per year

If you made any changes in Pure these will be visible here soon.

Personal profile

Research Interests

Preeclampsia, a maternal hypertensive condition, is a new risk factor for cardiovascular disease. Key proteins of interest in the disorder are vascular endothelial growth factor and its endogenous antagonist, soluble Flt-1 (sFlt-1). My research activity has focused on understanding their signaling transduction in endothelial cells and placenta. Previously I identified sFlt-1, which is elevated in pregnancies complicated with preeclampsia, as the principal factor responsible for the reduced placental angiogenesis associated with preeclampsia. Ongoing work is aimed at the development of novel in vivo models for preeclampsia and the use of transgenic animals to define how sFlt-1 causes preeclampsia-like condition. Specifically, I am interested in the interaction of these factors with pro-atherogenic chemokines and their role in the disease progression.

Contact Details

Education/Academic qualification

PG Cert

Award Date: 1 Sep 2017

PhD

Award Date: 1 Sep 2005

BSc, University of Kent

Award Date: 1 Sep 1999

Keywords

  • RG Gynecology and obstetrics
  • preeclampsia
  • vascular
  • placenta
  • RB Pathology
  • angiogenesis
  • heme oxygenase

Fingerprint

Dive into the research topics where Shakil Ahmad is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
  • 6 Similar Profiles

Network

Recent external collaboration on country level. Dive into details by clicking on the dots.
Your message has successfully been sent.
Your message was not sent due to an error.
If you made any changes in Pure these will be visible here soon.