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Personal profile

General

Dr Wang is a lecturer in Vascular Inflammation and Associate Dean for Research at Aston Medical School. Dr Wang’s postdoctoral research was funded by European Research Council and Medical Research Council. She has extensive research experience in immunology, inflammation and the vascular biology of pregnancy. Her current research interests focus on the role of gaseous transmitters in the pathogenesis of preeclampsia, fetal growth restriction and cardiomyopathy. She discovered hydrogen sulphide (H2S) as an important regulator of the placental vasculature development and showed that a deficiency in its production causes preeclampsia-like features. This study identified H2S as a potential new target for therapeutic intervention against preeclampsia and fetal growth restriction.This work was highlighted as being a “groundbreaking study” by Circulation and within the media (see: Breakthrough in fight against pre-eclampsia).

Research Interests

  • Pathogenesis of preeclampsia - research from basic science to preclinical experimental disease models and paves way to development of novel therapies for preeclampsia.
  • Diagnosis of preeclampsia and fetal growth restriction. Identify novel biomarkers including gaseous molecules, microRNAs and metabolites markers, protein modifications and laser devices.
  • Development of treatment for preeclampsia and fetal growth restriction.
  • Vascular homeostasis and chronic inflammation
  • Cardiomyopathy in pregnancy

Employment

2016 – present     Lecturer, Aston Medical School, Aston University, UK.

2014 – 2016   Aston Academic Research Fellow, Aston University, UK

2012 – 2014   MRC Postdoctoral Research Fellow, Aston University, UK.

2010 – 2012   MRC Postdoctoral Research Fellow, University of Edinburgh, UK. 

2008 – 2010   MRC Postdoctoral Research Fellow, University of Birmingham, UK. 

2002 - 2008    FP6 EU Postdoctoral Research Fellow, University of Birmingham, UK. 

2002               Research Associate, University of Birmingham, UK. 

1993 – 1996   Physician in Capital Pediatric Institution, Beijing, China.

Qualifications

PGCert (2017): Teaching & Learning in Higher Education. Aston University, UK

PhD (2002): Neutrophil spontaneous apoptosis and its regulation by type-I interferon. University of Birmingham, UK.

MSc (1998): Basic mechanism involved in human neutrophil apoptosis and their inhibition in the rheumatoid synovium.University of Birmingham, UK.

MD (1993):   General Medicine. Huazhong University of Science and Technology, China.

Administrative Roles

Assoicated Dean for Research at Aston Medical School since 2017

PhD Supervision

Primary supervisor for 2 PhD students from 2019-2022. 

Associated supervisor for 4 PhD students from 2016.

 

Education/Academic qualification

PG Cert

PhD

MSc

MD

1 Sep 19881 Jul 1993

Keywords

  • RG Gynecology and obstetrics
  • preeclampsia
  • fatal growth restriction
  • gaseous transmitters
  • cardiovascular
  • inflammation

Fingerprint Dive into the research topics where Keqing Wang is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 2 Similar Profiles
Pre-Eclampsia Medicine & Life Sciences
Hydrogen Sulfide Medicine & Life Sciences
Fetal Development Medicine & Life Sciences
Angiopoietin-1 Medicine & Life Sciences
Cystathionine beta-Synthase Medicine & Life Sciences
Neutrophils Medicine & Life Sciences
Phosphatidylinositol 3-Kinase Medicine & Life Sciences
Vascular Endothelial Growth Factor Receptor-1 Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2010 2018

333: Potential preeclampsia therapy tested

Ahmed, A., Wang, K., Ahmad, S. & Rezai, H., 3 Jan 2018, p. S208.

Research output: Contribution to conferencePoster

S100P enhances the motility and invasion of human trophoblast cell lines

Ebrahimzadeh Asl Tabrizi, M., Lancaster, T., Ismail, T. M., Ganguly, A., Georgiadou, A., Wang, K., Rudland, P. S., Ahmad, S. S. & Gross, S. R., 31 Jul 2018, In : Scientific Reports. 8, 11488.

Research output: Contribution to journalArticle

Open Access
File
Trophoblasts
First Pregnancy Trimester
Cell Movement
Physiological Phenomena
Cell Line

Angiopoietin-1 promotes atherosclerosis by increasing the proportion of circulating Gr1+ monocytes

Fujisawa, T., Wang, K., Niu, X-L., Egginton, S., Ahmad, S., Hewett, P. W., Kontos, C. D. & Ahmed, A., 17 Oct 2017, In : Cardiovascular Research. 113, 1, p. 81-89 9 p.

Research output: Contribution to journalArticle

Open Access
File
Angiopoietin-1
Monocytes
Atherosclerosis
Apolipoproteins E
Adenoviridae

Heterodimerisation between VEGFR-1 and VEGFR-2 and not the homodimers of VEGFR-1 inhibit VEGFR-2 activity

Cai, M., Wang, K., Murdoch, C. E., Gu, Y. & Ahmed, A., Jan 2017, In : Vascular Pharmacology. 88, p. 11-20 10 p.

Research output: Contribution to journalArticle

Open Access
File
Vascular Endothelial Growth Factor Receptor-1
Phosphatidylinositol 3-Kinase
Vascular Endothelial Growth Factor Receptor-2
Vascular Endothelial Growth Factor A
Phosphorylation

A pilot study using laser-based technique for non-invasive diagnostics of hypertensive conditions in mice

Choi, B. (ed.), Kollias, N. (ed.), Zeng, H. (ed.), Kang, H. W. (ed.), Wong, B. J. F. (ed.), Ilgner, J. F. (ed.), Tearney, G. J. (ed.), Gregory, K. W. (ed.), Marcu, L. (ed.), Skala, M. C. (ed.), Campagnola, P. J. (ed.), Mandelis, A. (ed.), Morris, M. D. (ed.), Litvinova, K. S., Ahmad, S., Wang, K., Rafailov, I. E., Sokolovski, S. G., Zhang, L., Rafailov, E. U. & 1 othersAhmed, A., 29 Feb 2016.

Research output: Contribution to conferenceOther

Open Access
File
Pre-Eclampsia
Lasers
Mothers
Equipment and Supplies
Aptitude