Photo of Alfred Fernandez-Castane

Alfred Fernandez-Castane

Dr, PhD in Biotechnology

    • School of Engineering and Applied Science, Aston University

      B4 7ET Birmingham

      United Kingdom

    Accepting PhD Students

    PhD projects

    NEW! Applications are invited for a 3-year funded PhD Studentship on "Microbial Bioprocessing and Functional Magnetic Materials". Email Dr Alfred Fernandez-Castane for detailed information at a.fernandez-castane1@aston.ac.uk. I am also willing to supervise PhD students in the following areas: - Microbial Biotechnology - Magnetotactic Bacteria - Biopolymers - Biomass conversion using enzyme and whole-cell biocatalysis - Biotechnology for biorefineries

    20102019
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    Research Output 2010 2019

    2019

    Unveiling magnetosome biomineralization in Magnetotactic Bacteria

    Fernandez-Castane, A. & Clarke-Bland, C., 30 Aug 2019, Biochemist, 41, 4, p. 58-59 2 p.

    Research output: Contribution to specialist publicationArticle

    Open Access
    Biomineralization
    Confocal microscopy
    Bacteria
    Experiments
    2018
    Open Access
    File
    Magnetospirillum
    Magnetosomes
    Fermentation
    Biomass
    Physiology
    Open Access
    File
    Adsorbents
    Feedstocks
    Immunoglobulins
    Immune Sera
    fishing
    2017
    Open Access
    File
    Magnetospirillum
    Flow Cytometry
    Iron
    Bacteria
    Magnetosomes
    2016

    Using flow cytometry to monitor cell physiology of magnetotactic bacteria in fermentation processes

    Fernández-castané, A., Li, H., Franzreb, M., Thomas, O. R. T. & Overton, T. W., 25 Jul 2016, In : New Biotechnology. 33, p. S19

    Research output: Contribution to journalMeeting abstract

    Using promoter libraries to reduce metabolic burden due to plasmid-encoded proteins in recombinant Escherichia coli

    Pasini, M., Fernández-castané, A., Jaramillo, A., De Mas, C., Caminal, G. & Ferrer, P., 25 Jan 2016, In : New Biotechnology. 33, 1, p. 78-90

    Research output: Contribution to journalArticle

    Open Access
    Recombinant Proteins
    Escherichia coli
    Libraries
    Repressor Proteins
    Plasmids
    2014

    Computer-aided design for metabolic engineering

    Fernández-castané, A., Fehér, T., Carbonell, P., Pauthenier, C. & Faulon, J., 1 Dec 2014, In : Journal of Biotechnology. 192, Part B, p. 302-313

    Research output: Contribution to journalArticle

    Metabolic engineering
    Metabolic Engineering
    Computer-Aided Design
    Genetic engineering
    Genetic Engineering

    Quantitative modeling of inducer transport in fed-batch cultures of Escherichia coli

    Calleja, D., Fernández-castañé, A., Pasini, M., De Mas, C. & López-santín, J., 1 Oct 2014, In : Biochemical Engineering Journal. 91, p. 210-219

    Research output: Contribution to journalArticle

    Fructose-Bisphosphate Aldolase
    Batch Cell Culture Techniques
    Escherichia coli
    Phosphates
    Theoretical Models

    Validation of RetroPath, a computer-aided design tool for metabolic pathway engineering

    Fehér, T., Planson, A., Carbonell, P., Fernández-castané, A., Grigoras, I., Dariy, E., Perret, A. & Faulon, J., 1 Nov 2014, In : Biotechnology Journal. 9, 11, p. 1446-1457

    Research output: Contribution to journalArticle

    Metabolic Engineering
    Computer-Aided Design
    Metabolic Networks and Pathways
    Enzymes
    Flavonoids
    2013

    From laboratory to pilot plant E. coli fed-batch cultures: optimizing the cellular environment for protein maximization

    Ruiz, J., Fernández-castané, A., De Mas, C., González, G. & López-santín, J., 1 Apr 2013, In : Journal of Industrial Microbiology & Biotechnology. 40, 3-4, p. 335-343

    Research output: Contribution to journalArticle

    Fructose-Bisphosphate Aldolase
    Batch Cell Culture Techniques
    Pilot plants
    Escherichia coli
    Proteins
    2012

    Direct measurements of IPTG enable analysis of the induction behavior of E. coli in high cell density cultures

    Fernández-castané, A., Caminal, G. & López-santín, J., 1 Jan 2012, In : Microbial Cell Factories. 11, 1, 58.

    Research output: Contribution to journalArticle

    Open Access
    File
    Isopropyl Thiogalactoside
    Lac Operon
    Biomass
    Escherichia coli
    Fructose-Bisphosphate Aldolase

    Evidencing the role of lactose permease in IPTG uptake by Escherichia coli in fed-batch high cell density cultures

    Fernández-castané, A., Vine, C. E., Caminal, G. & López-santín, J., 10 Feb 2012, In : Journal of Biotechnology. 157, 3, p. 391-398

    Research output: Contribution to journalArticle

    Isopropyl Thiogalactoside
    Escherichia coli
    Recombinant proteins
    Cell Culture Techniques
    Cell Count
    2010

    Development and Validation of a Liquid Chromatography-Mass Spectrometry Assay for the Quantitation of IPTG in E. Coli Fed-Batch Cultures

    Fernandez-Castane, A., Ruiz, J., Caminal, G. & López-santín, J., 1 Jul 2010, In : Analytical Chemistry. 82, 13, p. 5728-5734

    Research output: Contribution to journalArticle

    Liquid chromatography
    Recombinant Proteins
    Escherichia coli
    Mass spectrometry
    Assays