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Andrew Pitt

Professor

    19982020

    Research output per year

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    A comparison of five lipid extraction solvent systems for lipidomic studies of human LDL

    Reis, A., Rudnitskaya, A., Blackburn, G. J., Fauzi, N. M., Pitt, A. R. & Spickett, C. M., Jul 2013, In : Journal of Lipid Research. 54, 7, p. 1812-1824 13 p.

    Research output: Contribution to journalArticle

    A comparison of the effects of ocular preservatives on mammalian and microbial ATP and glutathione levels

    Ingram, P. R., Pitt, A. R., Wilson, C. G., Olejnik, O. & Spickett, C. M., Jul 2004, In : Free Radical Research. 38, 7, p. 739-750 12 p.

    Research output: Contribution to journalArticle

    A high-sensitivity electrochemiluminescence-based ELISA for the measurement of the oxidative stress biomarker, 3-nitrotyrosine, in human blood serum and cells

    Knight, A. R., Taylor, E., Lukaszewski, R., Tveen Jensen, K., Jones, H. E., Carré, J. E., supov, M. N. I., Littlechild, J. A., Bailey, S. J., Brewer, E., McDonald, T. J., Pitt, A. R., Spickett, C. M. & Winyard, P. G., 20 May 2018, In : Free Radical Biology and Medicine. 120, p. 246-254

    Research output: Contribution to journalArticle

    Open Access
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    Open Access
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    Analysis of SMALP co-extracted phospholipids shows distinct membrane environments for three classes of bacterial membrane protein

    Teo, A. C. K., Lee, S. C., Pollock, N. L., Stroud, Z., Hall, S., Thakker, A., Pitt, A. R., Dafforn, T. R., Spickett, C. M. & Roper, D. I., 12 Feb 2019, In : Scientific Reports. 9, 1, 1813.

    Research output: Contribution to journalArticle

    Open Access
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    A solvent-free matrix application method for matrix-assisted laser desorption/ionization imaging of small molecules

    Goodwin, R. J., Macintyre, L., Watson, D. G., Scullion, S. P. & Pitt, A., 15 Jun 2010, In : Rapid communications in mass spectrometry. 24, 11, p. 1682-1686 5 p.

    Research output: Contribution to journalArticle

    Characterisation of the plasma membrane subproteome of bloodstream form Trypanosoma brucei

    Bridges, D. J., Pitt, A. R., Hanrahan, O., Brennan, K., Voorheis, H. P., Herzyk, P., de Koning, H. P. & Burchmore, R. J. S., Jan 2008, In : Proteomics. 8, 1, p. 83-99 17 p.

    Research output: Contribution to journalArticle

    Open Access
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    Comprehensive human urine standards for comparability and standardization in clinical proteome analysis

    Mischak, H., Kolch, W., Aivaliotis, M., Bouyssié, D., Court, M., Dihazi, H., Dihazi, G. H., Franke, J., Garin, J., Gonzalez de Peredo, A., Iphöfer, A., Jänsch, L., Lacroix, C., Makridakis, M., Masselon, C., Metzger, J., Monsarrat, B., Mrug, M., Norling, M., Novak, J. & 11 others, Pich, A., Pitt, A., Bongcam-Rudloff, E., Siwy, J., Suzuki, H., Thongboonkerd, V., Wang, L-S., Zoidakis, J., Zürbig, P., Schanstra, J. P. & Vlahou, A., Apr 2010, In : Proteomics. 4, 4, p. 464-78 15 p.

    Research output: Contribution to journalArticle

    Corrigendum to "European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)" [Redox Biol. 13 (2017) 94-162]

    Egea, J., Fabregat, I., Frapart, Y. M., Ghezzi, P., Görlach, A., Kietzmann, T., Kubaichuk, K., Knaus, U. G., Lopez, M. G., Olaso-Gonzalez, G., Petry, A., Schulz, R., Vina, J., Winyard, P., Abbas, K., Ademowo, O. S., Afonso, C. B., Andreadou, I., Antelmann, H., Antunes, F. & 131 others, Aslan, M., Bachschmid, M. M., Barbosa, R. M., Belousov, V., Berndt, C., Bernlohr, D., Bertrán, E., Bindoli, A., Bottari, S. P., Brito, P. M., Carrara, G., Casas, A. I., Chatzi, A., Chondrogianni, N., Conrad, M., Cooke, M. S., Costa, J. G., Cuadrado, A., My-Chan Dang, P., De Smet, B., Debelec-Butuner, B., Dias, I. H. K., Dunn, J. D., Edson, A. J., El Assar, M., El-Benna, J., Ferdinandy, P., Fernandes, A. S., Fladmark, K. E., Förstermann, U., Giniatullin, R., Giricz, Z., Görbe, A., Griffiths, H., Hampl, V., Hanf, A., Herget, J., Hernansanz-Agustín, P., Hillion, M., Huang, J., Ilikay, S., Jansen-Dürr, P., Jaquet, V., Joles, J. A., Kalyanaraman, B., Kaminskyy, D., Karbaschi, M., Kleanthous, M., Klotz, L. O., Korac, B., Korkmaz, K. S., Koziel, R., Kračun, D., Krause, K. H., Křen, V., Krieg, T., Laranjinha, J., Lazou, A., Li, H., Martínez-Ruiz, A., Matsui, R., McBean, G. J., Meredith, S. P., Messens, J., Miguel, V., Mikhed, Y., Milisav, I., Milković, L., Miranda-Vizuete, A., Mojović, M., Monsalve, M., Mouthuy, P. A., Mulvey, J., Münzel, T., Muzykantov, V., Nguyen, I. T. N., Oelze, M., Oliveira, N. G., Palmeira, C. M., Papaevgeniou, N., Pavićević, A., Pedre, B., Peyrot, F., Phylactides, M., Pircalabioru, G. G., Pitt, A. R., Poulsen, H. E., Prieto, I., Rigobello, M. P., Robledinos-Antón, N., Rodríguez-Mañas, L., Rolo, A. P., Rousset, F., Ruskovska, T., Saraiva, N., Sasson, S., Schröder, K., Semen, K., Seredenina, T., Shakirzyanova, A., Smith, G. L., Soldati, T., Sousa, B. C., Spickett, C. M., Stancic, A., Stasia, M. J., Steinbrenner, H., Stepanić, V., Steven, S., Tokatlidis, K., Tuncay, E., Turan, B., Ursini, F., Vacek, J., Vajnerova, O., Valentová, K., Van Breusegem, F., Varisli, L., Veal, E. A., Yalçin, A. S., Yelisyeyeva, O., Žarković, N., Zatloukalová, M., Zielonka, J., Touyz, R. M., Papapetropoulos, A., Grune, T., Lamas, S., Schmidt, H. H. H. W., Di Lisa, F. & Daiber, A., 26 Oct 2017, In : Redox Biology. In press

    Research output: Contribution to journalArticle

    Open Access
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    Detection of phosphatidylserine with a modified polar head group in human keratinocytes exposed to the radical generator AAPH

    Maciel, E., Neves, B. M., Santinha, D., Reis, A., Domingues, P., Cruz, M. T., Pitt, A. R., Spickett, C. M. & Domingues, M. R. M., 15 Apr 2014, In : Archives of Biochemistry and Biophysics. 548, p. 38–45 8 p.

    Research output: Contribution to journalArticle

    Open Access
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    Detection of phospholipid oxidation in oxidatively stressed cells by reversed-phase HPLC coupled with positive-ionization electrospray MS

    Spickett, C. M., Rennie, N., Winter, H., Zambonin, L., Landi, L., Jerlich, A., Schaur, R. J. & Pitt, A. R., 15 Apr 2001, In : Biochemical Journal. 355, 2, p. 449-457 9 p.

    Research output: Contribution to journalArticle

    Development of novel mass spectrometric methods for identifying HOCl-induced modifications to proteins

    Mouls, L., Silajdzic, E., Haroune, N., Spickett, C. M. & Pitt, A. R., 1 Mar 2009, In : Proteomics. 9, 6, p. 1617-1631 15 p.

    Research output: Contribution to journalArticle

    Direct observation of lipid hydroperoxides in phospholipid vesicles by electrospray mass spectrometry

    Spickett, C. M., Pitt, A. R. & Brown, A. J., Sep 1998, In : Free Radical Biology and Medicine. 25, 4-5, p. 613-620 8 p.

    Research output: Contribution to journalArticle

    Effect of phosphatidylcholine chlorohydrins on human erythrocytes

    Robaszkiewicz, A., Greig, F. H., Pitt, A. R., Spickett, C. M., Bartosz, G. & Soszyński, M., Sep 2010, In : Chemistry and Physics of Lipids. 163, 7, p. 639-647 9 p.

    Research output: Contribution to journalArticle

    Epitope mapping and characterization of 4-hydroxy-2-nonenal modified-human serum albumin using two different polyclonal antibodies

    Campos-pinto, I., Méndez, L., Schouten, J., Wilkins, J., Fedorova, M., Pitt, A., Davis, P. & Spickett, C., 20 Nov 2019, In : Free Radical Biology and Medicine. 144, p. 234-244 11 p.

    Research output: Contribution to journalArticle

    Open Access
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    Eukaryotic translation initiation factor 3, subunit a, regulates the extracellular signal-regulated kinase pathway

    Xu, T-R., Lu, R-F., Romano, D., Pitt, A., Houslay, M. D., Milligan, G. & Kolch, W., Jan 2012, In : Molecular and Cellular Biology. 32, 1, p. 88-95 8 p.

    Research output: Contribution to journalArticle

    Open Access

    European contribution to the study of ROS: a summary of the findings and prospects for the future from the COST Action BM1203 (EU-ROS)

    Egea, J., Fabregat, I., Frapart, Y. M., Ghezzi, P., Görlach, A., Kietzmann, T., Kubaichuk, K., Knaus, U. G., Lopez, M. G., Olaso-Gonzalez, G., Petry, A., Schulz, R., Vina, J., Winyard, P., Abbas, K., Ademowo, S., Afonso, C. B., Andreadou, I., Antelmann, H., Antunes, F. & 131 others, Aslan, M., Bachschmid, M. M., Barbosa, R. M., Belousov, V., Berndt, C., Bernlohr, D., Bertrán, E., Bindoli, A., Bottari, S. P., Brito, P. M., Carrara, G., Casas, A. I., Chatzi, A., Chondrogianni, N., Conrad, M., Cooke, M. S., Costa, J. G., Cuadrado, A., My-Chan Dang, P., De Smet, B., Debelec–butuner, B., Dias, I., Dunn, J. D., Edson, A. J., El Assar, M., El-Benna, J., Ferdinandy, P., Fernandes, A. S., Fladmark, K. E., Förstermann, U., Giniatullin, R., Giricz, Z., Görbe, A., Griffiths, H., Hampl, V., Hanf, A., Herget, J., Hernansanz-Agustín, P., Hillion, M., Huang, J., Ilikay, S., Jansen-Dürr, P., Jaquet, V., Joles, J. A., Kalyanaraman, B., Kaminskyy, D., Karbaschi, M., Kleanthous, M., Klotz, L-O., Korac, B., Korkmaz, K. S., Koziel, R., Kračun, D., Krause, K-H., Křen, V., Krieg, T., Laranjinha, J., Lazou, A., Li, H., Martínez-Ruiz, A., Matsui, R., Mcbean, G. J., Meredith, S. P., Messens, J., Miguel, V., Mikhed, Y., Milisav, I., Milković, L., Miranda-Vizuete, A., Mojović, M., Monsalve, M., Mouthuy, P-A., Mulvey, J., Münzel, T., Muzykantov, V., Nguyen, I. T. N., Oelze, M., Oliveira, N. G., Palmeira, C. M., Papaevgeniou, N., Pavićević, A., Pedre, B., Peyrot, F., Phylactides, M., Pircalabioru, G. G., Pitt, A. R., Poulsen, H. E., Prieto, I., Rigobello, M. P., Robledinos-Antón, N., Rodríguez-mañas, L., Rolo, A. P., Rousset, F., Ruskovska, T., Saraiva, N., Sasson, S., Schröder, K., Semen, K., Seredenina, T., Shakirzyanova, A., Smith, G. L., Soldati, T., Sousa, B. C., Spickett, C. M., Stancic, A., Stasia, M. J., Steinbrenner, H., Stepanić, V., Steven, S., Tokatlidis, K., Tuncay, E., Turan, B., Ursini, F., Vacek, J., Vajnerova, O., Valentová, K., van Breusegem, F., Varisli, L., Veal, E. A., Yalçın, A. S., Yelisyeyeva, O., Žarković, N., Zatloukalová, M., Zielonka, J., Touyz, R. M., Papapetropoulos, A., Grune, T., Lamas, S., Schmidt, H. H. H. W., di Lisa, F. & Daiber, A., 1 Oct 2017, In : Redox biology. 13, p. 94-162 69 p.

    Research output: Contribution to journalArticle

    Open Access
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    Evaluation of air oxidized PAPC: A multi laboratory study by LC-MS/MS

    Ni, Z., Sousa, B. C., Colombo, S., Afonso, C. B., Melo, T., Pitt, A. R., Spickett, C. M., Domingues, P., Domingues, M. R., Fedorova, M. & Criscuolo, A., 20 Nov 2019, In : Free Radical Biology and Medicine. 144, p. 156-166 11 p.

    Research output: Contribution to journalArticle

    Open Access
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    Generation of primary hepatocyte microarrays by piezoelectric printing

    Zarowna-Dabrowska, A., McKenna, E. O., Schütte, M. E., Glidle, A., Chen, L., Cuestas-Ayllon, C., Marshall, D., Pitt, A., Dawson, M. D., Gu, E., Cooper, J. M. & Yin, H., 1 Jan 2012, In : Colloids and Surface B: Biointerfaces. 89, 1, p. 126-132 7 p.

    Research output: Contribution to journalArticle

    HOCl-modified phosphatidylcholines induce apoptosis and redox imbalance in HUVEC-ST cells

    Robaszkiewicz, A., Bartosz, G., Pitt, A. R., Thakker, A., Armstrong, R. A., Spickett, C. M. & Soszyński, M., 15 Apr 2014, In : Archives of Biochemistry and Biophysics. 548, p. 1-10 10 p.

    Research output: Contribution to journalArticle

    Open Access
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    Identification and relative quantification of tyrosine nitration in a model peptide using two-dimensional infrared spectroscopy

    Rezende Valim, L., Davies, J. A., Tveen Jensen, K., Guo, R., Willison, K. R., Spickett, C. M., Pitt, A. R. & Klug, D. R., 13 Nov 2014, In : Journal of Physical Chemistry: Part B. 118, 45, p. 12855-12864 10 p.

    Research output: Contribution to journalArticle

    Open Access
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    Incorporation of N-heterocyclic cations into proteins with a highly directed chemical modification

    McMillan, N., Smith, L. V., de la Fuente, J. M., Parenty, A. D. C., Gadegaard, N., Pitt, A. R., Thomson, K., Mackenzie, C., Kelly, S. M. & Cronin, L., May 2007, In : Chemical Communications. 2007, 25, p. 2581-3258 3 p.

    Research output: Contribution to journalArticle

    Increased production of 27-hydroxycholesterol in human colorectal cancer advanced stage: Possible contribution to cancer cell survival and infiltration

    Rossin, D., Dias, I. H. K., Solej, M., Milic, I., Pitt, A. R., Iaia, N., Scoppapietra, L., Devitt, A., Nano, M., Degiuli, M., Volante, M., Caccia, C., Leoni, V., Griffiths, H. R., Spickett, C. M., Poli, G. & Biasi, F., 20 May 2019, In : Free Radical Biology and Medicine. 136, p. 35-44 10 p.

    Research output: Contribution to journalArticle

    Open Access
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    Interfacing low-energy SAW nebulization with liquid chromatography-mass spectrometry for the analysis of biological samples

    Tveen Jensen, K., Gesellchen, F., Wilson, R., Spickett, C., Cooper, J. M. & Pitt, A., 15 May 2015, In : Scientific Reports. 5, 5 p., 9736.

    Research output: Contribution to journalArticle

    Open Access
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    Intracellular protein determination using droplet-based immunoassays

    Martino, C., Zagnoni, M., Sandison, M. E., Chanasakulniyom, M., Pitt, A. & Cooper, J. M., 16 May 2011, In : Analytical Chemistry. 83, 13, p. 5361-5368 8 p.

    Research output: Contribution to journalArticle

    Open Access

    Magnetite-doped polydimethylsiloxane (PDMS) for phosphopeptide enrichment

    Sandison, M. E., Tveen Jensen, K., Gesellchen, F., Cooper, J. M. & Pitt, A. R., 7 Oct 2014, In : Analyst. 139, 19, p. 4974-4981 8 p.

    Research output: Contribution to journalArticle

    Open Access
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    Mass spectrometry imaging of pharmacological compounds in tissue sections

    Goodwin, R. J. A. & Pitt, A. R., Feb 2010, In : Bioanalysis. 2, 2, p. 279-293 15 p.

    Research output: Contribution to journalArticle

    Matrix-free mass spectrometric imaging using laser desorption ionisation Fourier transform ion cyclotron resonance mass spectrometry

    Goodwin, R. J. A., Pitt, A. R., Harrison, D., Weidt, S. K., Langridge-Smith, P. R. R., Barrett, M. P. & Mackay, C. L., 15 Apr 2011, In : Rapid communications in mass spectrometry. 25, 7, p. 969-72 4 p.

    Research output: Contribution to journalArticle

    Open Access

    Microarray-formatted clinical biomarker assay development using peptide aptamers to anterior gradient-2

    Murray, E., McKenna, E. O., Burch, L. R., Dillon, J., Langridge-Smith, P., Kolch, W., Pitt, A. & Hupp, T. R., 4 Dec 2007, In : Biochemistry. 46, 48, p. 13742-13751 10 p.

    Research output: Contribution to journalArticle

    Microscale mesoarrays created by dip-pen nanolithography for screening of protein-protein interactions

    Thompson, D. G., McKenna, E. O., Pitt, A. & Graham, D., 15 Aug 2011, In : Biosensors and Bioelectronics. 26, 12, p. 4667-4673 7 p.

    Research output: Contribution to journalArticle

    Mutations of beta-arrestin 2 that limit self-association also interfere with interactions with the beta2-adrenoceptor and the ERK1/2 MAPKs: implications for beta2-adrenoceptor signalling via the ERK1/2 MAPKs

    Xu, T-R., Baillie, G. S., Bhari, N., Houslay, T. M., Pitt, A. M., Adams, D. R., Kolch, W., Houslay, M. D. & Milligan, G., 1 Jul 2008, In : Biochemical Journal. 413, 1, p. 51-60 10 p.

    Research output: Contribution to journalArticle

    On-chip immunoprecipitation for protein purification

    Sandison, M. E., Cumming, S. A., Kolch, W. & Pitt, A. R., 17 Aug 2010, In : Lab on a Chip. 2010, 20, p. 2805-2813 9 p.

    Research output: Contribution to journalArticle

    Open Access
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    PARP1 Co-regulates EP300–BRG1-dependent transcription of genes involved in breast cancer cell proliferation and DNA repair

    Sobczak, M., Pitt, A. R., Spickett, C. M. & Robaszkiewicz, A., 11 Oct 2019, In : Cancers. 11, 10, 1539.

    Research output: Contribution to journalArticle

    Open Access
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    Pathways of phospholipid oxidation by HOCL in human LDL detected by LC-MS

    Jerlich, A., Pitt, A. R., Schaur, R. J. & Spickett, C. M., 1 Mar 2000, In : Free Radical Biology and Medicine. 28, 5, p. 673-682 10 p.

    Research output: Contribution to journalArticle

    Performance of five different electrospray ionisation sources in conjunction with rapid monolithic column liquid chromatography and fast MS/MS scanning

    Burgess, K. E. V., Lainson, A., Imrie, L., Fraser-Pitt, D., Yaga, R., Smith, D. G. E., Swart, R., Pitt, A. R. & Inglis, N. F., Mar 2009, In : Proteomics. 9, 6, p. 1720-1726 7 p.

    Research output: Contribution to journalArticle

    Phospholipid chlorohydrins cause ATP depletion and toxicity in human myeloid cells

    Dever, G., Stewart, L-J., Pitt, A. & Spickett, C. M., 10 Apr 2003, In : FEBS Letters. 540, 1-3, p. 245-250 6 p.

    Research output: Contribution to journalArticle

    Open Access
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    Protein and peptides in pictures: imaging with MALDI mass spectrometry

    Goodwin, R. J. A., Pennington, S. R. & Pitt, A. R., 18 Sep 2008, In : Proteomics. 8, 18, p. 3785-3800 16 p.

    Research output: Contribution to journalArticle

    Protein oxidation: role in signalling and detection by mass spectrometry

    Spickett, C. M. & Pitt, A. R., Jan 2012, In : Amino Acids. 42, 1, p. 5-21 17 p.

    Research output: Contribution to journalArticle

    Proteomic analysis of phosphorylation, oxidation and nitrosylation in signal transduction

    Spickett, C. M., Pitt, A. R., Morrice, N. & Kolch, W., Dec 2006, In : BBA - Proteins and Proteomics. 1764, 12, p. 1823-1841 19 p.

    Research output: Contribution to journalArticle

    Proteomics in the study of hippocampal plasticity

    Cobb, S. R. & Pitt, A., Jun 2008, In : Expert Review of Proteomics. 5, 3, p. 393-404 12 p.

    Research output: Contribution to journalArticle

    Quantification of functionalised gold nanoparticle-targeted knockdown of gene expression in HeLa cells

    Jiwaji, M., Sandison, M. E., Reboud, J., Stevenson, R., Daly, R., Barkess, G., Faulds, K., Kolch, W., Graham, D., Girolami, M. A., Cooper, J. M. & Pitt, A., 13 Jun 2014, In : PLoS ONE. 9, 6, 10 p., e99458.

    Research output: Contribution to journalArticle

    Open Access
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    Raf kinase inhibitor protein RKIP enhances signaling by glycogen synthase kinase-3β

    Al-Mulla, F., Bitar, M. S., Al-Maghrebi, M., Behbehani, A. I., Al-Ali, W., Rath, O., Doyle, B., Tan, K. Y., Pitt, A. & Kolch, W., 15 Feb 2011, In : Cancer Research. 71, 4, p. 1334-1343 10 p.

    Research output: Contribution to journalArticle

    Open Access
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