1994 …2020

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A comparison of five lipid extraction solvent systems for lipidomic studies of human LDL

Reis, A., Rudnitskaya, A., Blackburn, G. J., Fauzi, N. M., Pitt, A. R. & Spickett, C. M., Jul 2013, In : Journal of Lipid Research. 54, 7, p. 1812-1824 13 p.

Research output: Contribution to journalArticle

A comparison of the effects of ocular preservatives on mammalian and microbial ATP and glutathione levels

Ingram, P. R., Pitt, A. R., Wilson, C. G., Olejnik, O. & Spickett, C. M., Jul 2004, In : Free Radical Research. 38, 7, p. 739-750 12 p.

Research output: Contribution to journalArticle

Advances in methods for the determination of biologically relevant lipid peroxidation products

Spickett, C. M., Wiswedel, I., Siems, W., Zarkovic, K. & Zarkovic, N., Oct 2010, In : Free Radical Research. 44, 10, p. 1172-1202 31 p.

Research output: Contribution to journalArticle

A high-fat meal induces low-grade endotoxemia: evidence of a novel mechanism of postprandial inflammation

Erridge, C., Attina, T., Spickett, C. M. & Webb, D. J., Nov 2007, In : American Journal of Clinical Nutrition. 86, 5, p. 1286-1292 7 p.

Research output: Contribution to journalArticle

A high-sensitivity electrochemiluminescence-based ELISA for the measurement of the oxidative stress biomarker, 3-nitrotyrosine, in human blood serum and cells

Knight, A. R., Taylor, E., Lukaszewski, R., Tveen Jensen, K., Jones, H. E., Carré, J. E., supov, M. N. I., Littlechild, J. A., Bailey, S. J., Brewer, E., McDonald, T. J., Pitt, A. R., Spickett, C. M. & Winyard, P. G., 20 May 2018, In : Free Radical Biology and Medicine. 120, p. 246-254

Research output: Contribution to journalArticle

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Alteration of the erythrocyte glutathione redox balance by N-acetylcysteine, captopril and exogenous glutathione

Russell, J., Spickett, C. M., Reglinski, J., Smith, W. E., McMurray, J. & Abdullah, I. B., 27 Jun 1994, In : FEBS Letters. 347, 2-3, p. 215-220 6 p.

Research output: Contribution to journalArticle

Open Access
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Analysis of oxidized and chlorinated lipids by mass spectrometry and relevance to signalling

Spickett, C. M. & Fauzi, N. M., Oct 2011, In : Biochemical Society Transactions. 39, 5, p. 1233-1239 7 p.

Research output: Contribution to journalArticle

Analysis of radicals and radical reaction products in cell signalling and biomolecular damage: the long hard road to gold-standard measures

Winyard, P. G., Spickett, C. M. & Griffiths, H. R., Oct 2011, In : Biochemical Society Transactions. 39, 5, p. 1217-1220 4 p.

Research output: Contribution to journalArticle

Analysis of SMALP co-extracted phospholipids shows distinct membrane environments for three classes of bacterial membrane protein

Teo, A. C. K., Lee, S. C., Pollock, N. L., Stroud, Z., Hall, S., Thakker, A., Pitt, A. R., Dafforn, T. R., Spickett, C. M. & Roper, D. I., 12 Feb 2019, In : Scientific Reports. 9, 1, 1813.

Research output: Contribution to journalArticle

Open Access
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An inter-laboratory validation of methods of lipid peroxidation measurement in UVA-treated human plasma samples

Breusing, N., Grune, T., Andrisic, L., Atalay, M., Bartosz, G., Biasi, F., Borovic, S., Bravo, L., Casals, I., Casillas, R., Dinischiotu, A., Drzewinska, J., Faber, H., Fauzi, N. M., Gajewska, A., Gambini, J., Gradinaru, D., Kokkola, T., Lojek, A., Łuczaj, W. & 16 others, Margina, D., Mascia, C., Mateos, R., Meinitzer, A., Mitjavila, M. T., Mrakovcic, L., Munteanu, M. C., Podborska, M., Poli, G., Sicinska, P., Skrzydlewska, E., Vina, J., Wiswedel, I., Zarkovic, N., Zelzer, S. & Spickett, C. M., Oct 2010, In : Free Radical Research. 44, 10, p. 1203-1215 13 p.

Research output: Contribution to journalArticle

Open Access

Anti-myeloperoxidase antibodies attenuate the monocyte response to LPS and shape macrophage development

Popat, R. J., Hakki, S., Thakker, A., Coughlan, A. M., Watson, J., Little, M. A., Spickett, C. M., Lavender, P., Afzali, B., Kemper, C. & Robson, M. G., 26 Jan 2017, In : JCI Insight. 2, 2, e87379.

Research output: Contribution to journalArticle

Open Access
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Open Access
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Chemistry of phospholipid oxidation

Reis Pereira, A. & Spickett, C. M., Oct 2012, In : BBA -Biomembranes. 1818, 10, p. 2374–2387 14 p.

Research output: Contribution to journalArticle

Chemometric modelling to relate antioxidants, neutral lipid fatty acids and flavour components in chicken breast

Jahan, K., Paterson, A., Piggott, J. & Spickett, C., 2005, In : Poultry Science. 84, 1, p. 158-166 9 p.

Research output: Contribution to journalArticle

Chlorinated lipids and fatty acids: an emerging role in pathology

Spickett, C. M., Sep 2007, In : Pharmacology and Therapeutics. 115, 3, p. 400-409 10 p.

Research output: Contribution to journalArticle

Copper complexes as a source of redox active MRI contrast agents

Dunbar, L., Sowden, R. J., Trotter, K. D., Taylor, M. K., Smith, D., Kennedy, A. R., Reglinski, J. & Spickett, C. M., 2015, In : BioMetals. 28, 5, p. 903-912 10 p.

Research output: Contribution to journalArticle

Open Access
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Copper N2S2 Schiff base macrocycles: the effect of structure on redox potential

Taylor, M. K., Trotter, K. D., Reglinski, J., Berlouis, L. E. A., Kennedy, A. R., Spickett, C. M. & Sowden, R. J., 27 Jun 2008, In : Inorganica Chimica Acta. 361, 9-10, p. 2851-2862 12 p.

Research output: Contribution to journalArticle

Corrigendum to "European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)" [Redox Biol. 13 (2017) 94-162]

Egea, J., Fabregat, I., Frapart, Y. M., Ghezzi, P., Görlach, A., Kietzmann, T., Kubaichuk, K., Knaus, U. G., Lopez, M. G., Olaso-Gonzalez, G., Petry, A., Schulz, R., Vina, J., Winyard, P., Abbas, K., Ademowo, O. S., Afonso, C. B., Andreadou, I., Antelmann, H., Antunes, F. & 131 others, Aslan, M., Bachschmid, M. M., Barbosa, R. M., Belousov, V., Berndt, C., Bernlohr, D., Bertrán, E., Bindoli, A., Bottari, S. P., Brito, P. M., Carrara, G., Casas, A. I., Chatzi, A., Chondrogianni, N., Conrad, M., Cooke, M. S., Costa, J. G., Cuadrado, A., My-Chan Dang, P., De Smet, B., Debelec-Butuner, B., Dias, I. H. K., Dunn, J. D., Edson, A. J., El Assar, M., El-Benna, J., Ferdinandy, P., Fernandes, A. S., Fladmark, K. E., Förstermann, U., Giniatullin, R., Giricz, Z., Görbe, A., Griffiths, H., Hampl, V., Hanf, A., Herget, J., Hernansanz-Agustín, P., Hillion, M., Huang, J., Ilikay, S., Jansen-Dürr, P., Jaquet, V., Joles, J. A., Kalyanaraman, B., Kaminskyy, D., Karbaschi, M., Kleanthous, M., Klotz, L. O., Korac, B., Korkmaz, K. S., Koziel, R., Kračun, D., Krause, K. H., Křen, V., Krieg, T., Laranjinha, J., Lazou, A., Li, H., Martínez-Ruiz, A., Matsui, R., McBean, G. J., Meredith, S. P., Messens, J., Miguel, V., Mikhed, Y., Milisav, I., Milković, L., Miranda-Vizuete, A., Mojović, M., Monsalve, M., Mouthuy, P. A., Mulvey, J., Münzel, T., Muzykantov, V., Nguyen, I. T. N., Oelze, M., Oliveira, N. G., Palmeira, C. M., Papaevgeniou, N., Pavićević, A., Pedre, B., Peyrot, F., Phylactides, M., Pircalabioru, G. G., Pitt, A. R., Poulsen, H. E., Prieto, I., Rigobello, M. P., Robledinos-Antón, N., Rodríguez-Mañas, L., Rolo, A. P., Rousset, F., Ruskovska, T., Saraiva, N., Sasson, S., Schröder, K., Semen, K., Seredenina, T., Shakirzyanova, A., Smith, G. L., Soldati, T., Sousa, B. C., Spickett, C. M., Stancic, A., Stasia, M. J., Steinbrenner, H., Stepanić, V., Steven, S., Tokatlidis, K., Tuncay, E., Turan, B., Ursini, F., Vacek, J., Vajnerova, O., Valentová, K., Van Breusegem, F., Varisli, L., Veal, E. A., Yalçin, A. S., Yelisyeyeva, O., Žarković, N., Zatloukalová, M., Zielonka, J., Touyz, R. M., Papapetropoulos, A., Grune, T., Lamas, S., Schmidt, H. H. H. W., Di Lisa, F. & Daiber, A., 26 Oct 2017, In : Redox Biology. In press

Research output: Contribution to journalArticle

Open Access
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Detection of phosphatidylserine with a modified polar head group in human keratinocytes exposed to the radical generator AAPH

Maciel, E., Neves, B. M., Santinha, D., Reis, A., Domingues, P., Cruz, M. T., Pitt, A. R., Spickett, C. M. & Domingues, M. R. M., 15 Apr 2014, In : Archives of Biochemistry and Biophysics. 548, p. 38–45 8 p.

Research output: Contribution to journalArticle

Open Access
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Detection of phospholipid oxidation in oxidatively stressed cells by reversed-phase HPLC coupled with positive-ionization electrospray MS

Spickett, C. M., Rennie, N., Winter, H., Zambonin, L., Landi, L., Jerlich, A., Schaur, R. J. & Pitt, A. R., 15 Apr 2001, In : Biochemical Journal. 355, 2, p. 449-457 9 p.

Research output: Contribution to journalArticle

Development of novel mass spectrometric methods for identifying HOCl-induced modifications to proteins

Mouls, L., Silajdzic, E., Haroune, N., Spickett, C. M. & Pitt, A. R., 1 Mar 2009, In : Proteomics. 9, 6, p. 1617-1631 15 p.

Research output: Contribution to journalArticle

Differential effects of chlorinated and oxidized phospholipids in vascular tissue: implications for neointima formation

Greig, F. H., Hutchison, L., Spickett, C. M. & Kennedy, S., 1 May 2015, In : Clinical Science. 128, 9, p. 579-592 14 p.

Research output: Contribution to journalArticle

Open Access
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Dimethylsulfoxide oxidizes glutathione in vitro and in human erythrocytes: kinetic analysis by 1H NMR

Homer, N. Z. M., Reglinski, J., Sowden, R., Spickett, C. M., Wilson, R. & Walker, J. J., Jun 2005, In : Cryobiology. 50, 3, p. 317-324 8 p.

Research output: Contribution to journalArticle

Direct observation of lipid hydroperoxides in phospholipid vesicles by electrospray mass spectrometry

Spickett, C. M., Pitt, A. R. & Brown, A. J., Sep 1998, In : Free Radical Biology and Medicine. 25, 4-5, p. 613-620 8 p.

Research output: Contribution to journalArticle

Effect of phosphatidylcholine chlorohydrins on human erythrocytes

Robaszkiewicz, A., Greig, F. H., Pitt, A. R., Spickett, C. M., Bartosz, G. & Soszyński, M., Sep 2010, In : Chemistry and Physics of Lipids. 163, 7, p. 639-647 9 p.

Research output: Contribution to journalArticle

Epitope mapping and characterization of 4-hydroxy-2-nonenal modified-human serum albumin using two different polyclonal antibodies

Campos-pinto, I., Méndez, L., Schouten, J., Wilkins, J., Fedorova, M., Pitt, A., Davis, P. & Spickett, C., 20 Nov 2019, In : Free Radical Biology and Medicine. 144, p. 234-244 11 p.

Research output: Contribution to journalArticle

Open Access
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Erythrocyte glutathione balance and membrane stability during preeclampsia

Spickett, C. M., Reglinski, J., Smith, W. E., Wilson, R., Walker, J. J. & McKillop, J., Apr 1998, In : Free Radical Biology and Medicine. 24, 6, p. 1049-1055 7 p.

Research output: Contribution to journalArticle

European contribution to the study of ROS: a summary of the findings and prospects for the future from the COST Action BM1203 (EU-ROS)

Egea, J., Fabregat, I., Frapart, Y. M., Ghezzi, P., Görlach, A., Kietzmann, T., Kubaichuk, K., Knaus, U. G., Lopez, M. G., Olaso-Gonzalez, G., Petry, A., Schulz, R., Vina, J., Winyard, P., Abbas, K., Ademowo, S., Afonso, C. B., Andreadou, I., Antelmann, H., Antunes, F. & 131 others, Aslan, M., Bachschmid, M. M., Barbosa, R. M., Belousov, V., Berndt, C., Bernlohr, D., Bertrán, E., Bindoli, A., Bottari, S. P., Brito, P. M., Carrara, G., Casas, A. I., Chatzi, A., Chondrogianni, N., Conrad, M., Cooke, M. S., Costa, J. G., Cuadrado, A., My-Chan Dang, P., De Smet, B., Debelec–butuner, B., Dias, I., Dunn, J. D., Edson, A. J., El Assar, M., El-Benna, J., Ferdinandy, P., Fernandes, A. S., Fladmark, K. E., Förstermann, U., Giniatullin, R., Giricz, Z., Görbe, A., Griffiths, H., Hampl, V., Hanf, A., Herget, J., Hernansanz-Agustín, P., Hillion, M., Huang, J., Ilikay, S., Jansen-Dürr, P., Jaquet, V., Joles, J. A., Kalyanaraman, B., Kaminskyy, D., Karbaschi, M., Kleanthous, M., Klotz, L-O., Korac, B., Korkmaz, K. S., Koziel, R., Kračun, D., Krause, K-H., Křen, V., Krieg, T., Laranjinha, J., Lazou, A., Li, H., Martínez-Ruiz, A., Matsui, R., Mcbean, G. J., Meredith, S. P., Messens, J., Miguel, V., Mikhed, Y., Milisav, I., Milković, L., Miranda-Vizuete, A., Mojović, M., Monsalve, M., Mouthuy, P-A., Mulvey, J., Münzel, T., Muzykantov, V., Nguyen, I. T. N., Oelze, M., Oliveira, N. G., Palmeira, C. M., Papaevgeniou, N., Pavićević, A., Pedre, B., Peyrot, F., Phylactides, M., Pircalabioru, G. G., Pitt, A. R., Poulsen, H. E., Prieto, I., Rigobello, M. P., Robledinos-Antón, N., Rodríguez-mañas, L., Rolo, A. P., Rousset, F., Ruskovska, T., Saraiva, N., Sasson, S., Schröder, K., Semen, K., Seredenina, T., Shakirzyanova, A., Smith, G. L., Soldati, T., Sousa, B. C., Spickett, C. M., Stancic, A., Stasia, M. J., Steinbrenner, H., Stepanić, V., Steven, S., Tokatlidis, K., Tuncay, E., Turan, B., Ursini, F., Vacek, J., Vajnerova, O., Valentová, K., van Breusegem, F., Varisli, L., Veal, E. A., Yalçın, A. S., Yelisyeyeva, O., Žarković, N., Zatloukalová, M., Zielonka, J., Touyz, R. M., Papapetropoulos, A., Grune, T., Lamas, S., Schmidt, H. H. H. W., di Lisa, F. & Daiber, A., 1 Oct 2017, In : Redox biology. 13, p. 94-162 69 p.

Research output: Contribution to journalArticle

Open Access
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Evaluation of air oxidized PAPC: A multi laboratory study by LC-MS/MS

Ni, Z., Sousa, B. C., Colombo, S., Afonso, C. B., Melo, T., Pitt, A. R., Spickett, C. M., Domingues, P., Domingues, M. R., Fedorova, M. & Criscuolo, A., 20 Nov 2019, In : Free Radical Biology and Medicine. 144, p. 156-166 11 p.

Research output: Contribution to journalArticle

Open Access
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Exploring oxidative modifications of tyrosine: an update on mechanisms of formation, advances in analysis and biological consequences

Houée-Lévin, C., Bobrowski, K., Horakova, L., Karademir, B., Schöneich, C., Davies, M. J. & Spickett, C. M., 2015, In : Free Radical Research. 49, 4, p. 347-373 27 p.

Research output: Contribution to journalArticle

Open Access
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Fatty acid and phospholipid chlorohydrins cause cell stress and endothelial adhesion

Dever, G., Wainwright, C. L., Kennedy, S. & Spickett, C. M., 2006, In : Acta Biochimica Polonica. 53, 4, p. 761-768 8 p.

Research output: Contribution to journalArticle

Fatty acid composition, antioxidants and lipid oxidation in chicken breasts from different production regimes

Jahan, K., Paterson, A. & Spickett, C. M., Apr 2004, In : International Journal of Food Science and Technology. 39, 4, p. 443-453 11 p.

Research output: Contribution to journalArticle

H-1 nmr as a non-invasive probe of amniotic fluid in insulin dependant diabetes mellitus

McGowan, P. E., Lawrie, W. C., Reglinski, J., Spickett, C. M., Wilson, R., Walker, J. J., Wisdom, S. & MacLean, M. A., 1999, In : Journal of Perinatal Medicine. 27, 5, p. 404-408 5 p.

Research output: Contribution to journalArticle

HOCl-modified phosphatidylcholines induce apoptosis and redox imbalance in HUVEC-ST cells

Robaszkiewicz, A., Bartosz, G., Pitt, A. R., Thakker, A., Armstrong, R. A., Spickett, C. M. & Soszyński, M., 15 Apr 2014, In : Archives of Biochemistry and Biophysics. 548, p. 1-10 10 p.

Research output: Contribution to journalArticle

Open Access
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Identification and relative quantification of tyrosine nitration in a model peptide using two-dimensional infrared spectroscopy

Rezende Valim, L., Davies, J. A., Tveen Jensen, K., Guo, R., Willison, K. R., Spickett, C. M., Pitt, A. R. & Klug, D. R., 13 Nov 2014, In : Journal of Physical Chemistry: Part B. 118, 45, p. 12855-12864 10 p.

Research output: Contribution to journalArticle

Open Access
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Impairment of calcium ATPases by high glucose and potential pharmacological protection

Horáková, L., Strosova, M. K., Spickett, C. M. & Blaskovic, D., Aug 2013, In : Free Radical Research. 47, S1, p. 81-92 12 p.

Research output: Contribution to journalArticle

Increased production of 27-hydroxycholesterol in human colorectal cancer advanced stage: Possible contribution to cancer cell survival and infiltration

Rossin, D., Dias, I. H. K., Solej, M., Milic, I., Pitt, A. R., Iaia, N., Scoppapietra, L., Devitt, A., Nano, M., Degiuli, M., Volante, M., Caccia, C., Leoni, V., Griffiths, H. R., Spickett, C. M., Poli, G. & Biasi, F., 20 May 2019, In : Free Radical Biology and Medicine. 136, p. 35-44 10 p.

Research output: Contribution to journalArticle

Open Access
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Interfacing low-energy SAW nebulization with liquid chromatography-mass spectrometry for the analysis of biological samples

Tveen Jensen, K., Gesellchen, F., Wilson, R., Spickett, C., Cooper, J. M. & Pitt, A., 15 May 2015, In : Scientific Reports. 5, 5 p., 9736.

Research output: Contribution to journalArticle

Open Access
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Ligand-induced conformational changes in a SMALP-encapsulated GPCR.

Routledge, S. J., Jamshad, M., Little, H. A., Lin, Y. P., Simms, J., Thakker, A., Spickett, C. M., Bill, R. M., Dafforn, T. R., Poyner, D. R. & Wheatley, M., 1 Jun 2020, In : Biochimica et Biophysica Acta - Biomembranes. 1862, 6, 183235.

Research output: Contribution to journalArticle

Open Access
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Lipoproteins as targets and markers of lipoxidation

Afonso, C. B. & Spickett, C. M., 1 May 2019, In : Redox Biology. 23, 101066.

Research output: Contribution to journalArticle

Open Access
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Lipoxidation adducts with peptides and proteins: deleterious modifications or signalling mechanisms?

Domingues, M. R., Domingues, P., Melo, T., Pérez-Sala, D., Reis, A. & Spickett, C. M., 30 Oct 2013, In : Journal of Proteomics. 92, p. 110-131 22 p.

Research output: Contribution to journalArticle

Modulation of sarcoplasmic/endoplasmic reticulum Ca(2+)-ATPase activity and oxidative modification during the development of adjuvant arthritis

Strosova, M. K., Karlovska, J., Zizkova, P., Kwolek-Mirek, M., Ponist, S., Spickett, C. M. & Horakova, L., Jul 2011, In : Archives of Biochemistry and Biophysics. 511, 1-2, p. 40-47 8 p.

Research output: Contribution to journalArticle

Modulation of SERCA in the chronic phase of adjuvant arthritis as a possible adaptation mechanism of redox imbalance

Strosova, M., Karlovska, J., Spickett, C. M., Orszagova, Z., Ponist, S., Bauerova, K., Mihalova, D. & Horakova, L., Sep 2009, In : Free Radical Research. 43, 9, p. 852-864 13 p.

Research output: Contribution to journalArticle

Non-enterobacterial endotoxins stimulate human coronary artery but not venous endothelial cell activation via toll-like receptor 2

Erridge, C., Spickett, C. M. & Webb, D. J., 1 Jan 2007, In : Cardiovascular Research. 73, 1, p. 181-189 9 p.

Research output: Contribution to journalArticle

Oxidation of erythrocyte glutathione by monocytes stimulated with interleukin-6   : analysis by 1H spin echo NMR

Spickett, C. M., Smith, W. E., Reglinski, J., Wilson, R. & Walker, J. J., 23 Feb 1998, In : Clinica Chimica Acta. 270, 2, p. 115-124 10 p.

Research output: Contribution to journalArticle